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A unique allosteric insulin receptor monoclonal antibody that prevents hypoglycemia in the SUR-1-/- mouse model of KATP hyperinsulinism.
Patel, Puja; Charles, Lawrenshey; Corbin, John; Goldfine, Ira D; Johnson, Kirk; Rubin, Paul; De León, Diva D.
Afiliação
  • Patel P; a Division of Endocrinology, Department of Pediatrics , The Children's Hospital of Philadelphia , Philadelphia , Pennsylvania.
  • Charles L; a Division of Endocrinology, Department of Pediatrics , The Children's Hospital of Philadelphia , Philadelphia , Pennsylvania.
  • Corbin J; b XOMA Corporation , Berkeley , California.
  • Goldfine ID; c Department of Medicine , University of California San Francisco , San Francisco , California.
  • Johnson K; b XOMA Corporation , Berkeley , California.
  • Rubin P; b XOMA Corporation , Berkeley , California.
  • De León DD; a Division of Endocrinology, Department of Pediatrics , The Children's Hospital of Philadelphia , Philadelphia , Pennsylvania.
MAbs ; 10(5): 796-802, 2018 07.
Article em En | MEDLINE | ID: mdl-29589989
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptor de Insulina / Modelos Animais de Doenças / Canais KATP / Hiperinsulinismo / Hipoglicemia / Anticorpos Monoclonais Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptor de Insulina / Modelos Animais de Doenças / Canais KATP / Hiperinsulinismo / Hipoglicemia / Anticorpos Monoclonais Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2018 Tipo de documento: Article