A Strategy To Isolate Modifiers of <i>Caenorhabditis elegans</i> Lethal Mutations: Investigating the Endoderm Specifying Ability of the Intestinal Differentiation GATA Factor ELT-2.

Wiesenfahrt, Tobias; Duanmu, Jingjie; Snider, Frances; Moerman, Don; Au, Vinci; Li-Leger, Erica; Flibotte, Stephane; Parker, Dylan M; Marshall, Craig J; Nishimura, Erin Osborne; Mains, Paul E; McGhee, James D

A Strategy To Isolate Modifiers of Caenorhabditis elegans Lethal Mutations: Investigating the Endoderm Specifying Ability of the Intestinal Differentiation GATA Factor ELT-2.

Wiesenfahrt, Tobias; Duanmu, Jingjie; Snider, Frances; Moerman, Don; Au, Vinci; Li-Leger, Erica; Flibotte, Stephane; Parker, Dylan M; Marshall, Craig J; Nishimura, Erin Osborne; Mains, Paul E; McGhee, James D.

Afiliação

Wiesenfahrt T; Department of Biochemistry and Molecular Biology, Alberta Children's Hospital Research Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada T2N 4N1.
Duanmu J; Department of Biochemistry and Molecular Biology, Alberta Children's Hospital Research Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada T2N 4N1.
Snider F; Department of Biochemistry and Molecular Biology, Alberta Children's Hospital Research Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada T2N 4N1.
Moerman D; Department of Zoology and Michael Smith Laboratories, University of British Columbia, Vancouver, British Columbia, Canada V6T 1Z4.
Au V; Department of Zoology and Michael Smith Laboratories, University of British Columbia, Vancouver, British Columbia, Canada V6T 1Z4.
Li-Leger E; Department of Zoology and Michael Smith Laboratories, University of British Columbia, Vancouver, British Columbia, Canada V6T 1Z4.
Flibotte S; Department of Zoology and Michael Smith Laboratories, University of British Columbia, Vancouver, British Columbia, Canada V6T 1Z4.
Parker DM; Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, Colorado 80523.
Marshall CJ; Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, Colorado 80523.
Nishimura EO; Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, Colorado 80523.
Mains PE; Department of Biochemistry and Molecular Biology, Alberta Children's Hospital Research Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada T2N 4N1.
McGhee JD; Department of Biochemistry and Molecular Biology, Alberta Children's Hospital Research Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada T2N 4N1 jmcghee@ucalgary.ca.

G3 (Bethesda) ; 8(5): 1425-1437, 2018 05 04.

Article em En | MEDLINE | ID: mdl-29593072

Assuntos

Proteínas de Caenorhabditis elegans/genética; Caenorhabditis elegans/genética; Diferenciação Celular; Endoderma/metabolismo; Fatores de Transcrição GATA/genética; Genes Modificadores; Intestinos/citologia; Mutação/genética; Sequência de Aminoácidos; Animais; Caenorhabditis elegans/embriologia; Proteínas de Caenorhabditis elegans/química; Proteínas de Caenorhabditis elegans/metabolismo; Diferenciação Celular/genética; Embrião não Mamífero/metabolismo; Fatores de Transcrição GATA/química; Fatores de Transcrição GATA/metabolismo; Testes Genéticos; Genótipo; Reprodutibilidade dos Testes; Análise de Sobrevida; Sequenciamento Completo do Genoma; Zigoto/metabolismo

Palavras-chave

C. elegans; ELT-2 GATA factor; Mutant Screen Report; endoderm specification; intestine; pqn-82; tasp-1; taspase

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Diferenciação Celular / Caenorhabditis elegans / Proteínas de Caenorhabditis elegans / Endoderma / Fatores de Transcrição GATA / Genes Modificadores / Intestinos / Mutação Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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