Modulation of diabetes-related liver injury by the HMGB1/TLR4 inflammatory pathway.

Jovanovic Stojanov, Sofija; Martinovic, Vesna; Bogojevic, Desanka; Poznanovic, Goran; Petrovic, Anja; Ivanovic-Matic, Svetlana; Grigorov, Ilijana

Jovanovic Stojanov, Sofija; Martinovic, Vesna; Bogojevic, Desanka; Poznanovic, Goran; Petrovic, Anja; Ivanovic-Matic, Svetlana; Grigorov, Ilijana.

Afiliação

Jovanovic Stojanov S; Department of Molecular Biology, Institute for Biological Research "Sinisa Stankovic", University of Belgrade, Bulevar despota Stefana 142, Belgrade, 11060, Republic of Serbia.
Martinovic V; Department of Molecular Biology, Institute for Biological Research "Sinisa Stankovic", University of Belgrade, Bulevar despota Stefana 142, Belgrade, 11060, Republic of Serbia.
Bogojevic D; Department of Molecular Biology, Institute for Biological Research "Sinisa Stankovic", University of Belgrade, Bulevar despota Stefana 142, Belgrade, 11060, Republic of Serbia.
Poznanovic G; Department of Molecular Biology, Institute for Biological Research "Sinisa Stankovic", University of Belgrade, Bulevar despota Stefana 142, Belgrade, 11060, Republic of Serbia.
Petrovic A; Department of Molecular Biology, Institute for Biological Research "Sinisa Stankovic", University of Belgrade, Bulevar despota Stefana 142, Belgrade, 11060, Republic of Serbia.
Ivanovic-Matic S; Department of Molecular Biology, Institute for Biological Research "Sinisa Stankovic", University of Belgrade, Bulevar despota Stefana 142, Belgrade, 11060, Republic of Serbia.
Grigorov I; Department of Molecular Biology, Institute for Biological Research "Sinisa Stankovic", University of Belgrade, Bulevar despota Stefana 142, Belgrade, 11060, Republic of Serbia. iligri@ibiss.bg.ac.rs.

J Physiol Biochem ; 74(2): 345-358, 2018 May.

Article em En | MEDLINE | ID: mdl-29611132

Assuntos

Diabetes Mellitus Experimental/complicações; Proteína HMGB1/metabolismo; Inflamação/metabolismo; Hepatopatias/complicações; Receptor 4 Toll-Like/metabolismo; Animais; Biomarcadores/metabolismo; Diabetes Mellitus Experimental/metabolismo; Diabetes Mellitus Experimental/patologia; Haptoglobinas/metabolismo; Heme Oxigenase (Desciclizante)/metabolismo; Humanos; Interleucina-6/metabolismo; Hepatopatias/metabolismo; Hepatopatias/patologia; Sistema de Sinalização das MAP Quinases; Masculino; Fator 2 Relacionado a NF-E2/metabolismo; Proteínas Quinases/metabolismo; Piruvatos/farmacologia; Ratos Wistar; Estreptozocina; Fator de Necrose Tumoral alfa/metabolismo

Palavras-chave

Diabetes; Ethyl pyruvate; HMGB1/TLR4 signaling; Inflammatory response; Liver

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteína HMGB1 / Diabetes Mellitus Experimental / Receptor 4 Toll-Like / Inflamação / Hepatopatias Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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