All-trans retinoic acid in combination with sodium butyrate enhances specific monoclonal antibody productivity in recombinant CHO cell line.

Rahimi-Zarchi, Mahmood; Shojaosadati, Seyed Abbas; Amiri, Mohammad Mehdi; Jeddi-Tehrani, Mahmood; Shokri, Fazel

Rahimi-Zarchi, Mahmood; Shojaosadati, Seyed Abbas; Amiri, Mohammad Mehdi; Jeddi-Tehrani, Mahmood; Shokri, Fazel.

Afiliação

Rahimi-Zarchi M; Biotechnology Group, Faculty of Chemical Engineering, Tarbiat Modares University, Tehran, Iran.
Shojaosadati SA; Biotechnology Group, Faculty of Chemical Engineering, Tarbiat Modares University, Tehran, Iran. shoja_sa@modares.ac.ir.
Amiri MM; Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Jeddi-Tehrani M; Monoclonal Antibody Research Center, Avicenna Research Institute, ACECR, Tehran, Iran.
Shokri F; Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran. fshokri@tums.ac.ir.

Bioprocess Biosyst Eng ; 41(7): 961-971, 2018 Jul.

Article em En | MEDLINE | ID: mdl-29619548

Assuntos

Anticorpos Monoclonais/biossíntese; Ácido Butírico/farmacologia; Tretinoína/farmacologia; Animais; Anticorpos Monoclonais/genética; Células CHO; Técnicas de Cultura de Células; Cricetulus; Proteínas Recombinantes/biossíntese; Proteínas Recombinantes/genética

Palavras-chave

All-trans retinoic acid; CHO cells; Cell specific productivity (Q p); Monoclonal antibody; Sodium butyrate

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tretinoína / Ácido Butírico / Anticorpos Monoclonais Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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