Intratumoral administration of carboplatin bearing poly (Îµ-caprolactone) nanoparticles amalgamated with in situ gel tendered augmented drug delivery, cytotoxicity, and apoptosis in melanoma tumor.

Bragta, Pallvi; Sidhu, Rupinder Kaur; Jyoti, Kiran; Baldi, Ashish; Jain, Upendra Kumar; Chandra, Ramesh; Madan, Jitender

Bragta, Pallvi; Sidhu, Rupinder Kaur; Jyoti, Kiran; Baldi, Ashish; Jain, Upendra Kumar; Chandra, Ramesh; Madan, Jitender.

Afiliação

Bragta P; Department of Pharmaceutics, Chandigarh College of Pharmacy, Mohali, Punjab, India.
Sidhu RK; Department of Pharmaceutics, Chandigarh College of Pharmacy, Mohali, Punjab, India.
Jyoti K; Department of Pharmaceutics, Sachdeva College of Pharmacy, Mohali, Punjab, India.
Baldi A; Department of Pharmaceutical Science and Technology, Maharaja Ranjit Singh Punjab Technical University, Bathinda, Punjab, India.
Jain UK; Department of Pharmaceutics, Chandigarh College of Pharmacy, Mohali, Punjab, India.
Chandra R; Dr B.R Ambedkar Centre for Biomedical Research, University of Delhi, Delhi, India; Department of Chemistry, University of Delhi, Delhi, India.
Madan J; Department of Pharmaceutics, Chandigarh College of Pharmacy, Mohali, Punjab, India. Electronic address: jitenderpharmacy@gmail.com.

Colloids Surf B Biointerfaces ; 166: 339-348, 2018 Jun 01.

Article em En | MEDLINE | ID: mdl-29627747

Assuntos

Carboplatina/química; Nanopartículas/química; Poliésteres/química; Apoptose; Linhagem Celular Tumoral; Portadores de Fármacos/química; Sistemas de Liberação de Medicamentos/métodos; Humanos

Palavras-chave

Apoptosis; Carboplatin; Chitosan-ß-glycerophosphate in situ gel; Cytotoxicity; Poly(Îµ-caprolactone) nanoparticles; Preclinical analysis

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Poliésteres / Carboplatina / Nanopartículas Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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