KLF2-mediated disruption of PPAR-Î³ signaling in lymphatic endothelial cells exposed to chronically increased pulmonary lymph flow.

Morris, Catherine J; Kameny, Rebecca J; Boehme, Jason; Gong, Wenhui; He, Youping; Zhu, Terry; Maltepe, Emin; Raff, Gary W; Fineman, Jeffrey R; Datar, Sanjeev A

Morris, Catherine J; Kameny, Rebecca J; Boehme, Jason; Gong, Wenhui; He, Youping; Zhu, Terry; Maltepe, Emin; Raff, Gary W; Fineman, Jeffrey R; Datar, Sanjeev A.

Afiliação

Morris CJ; Department of Pediatrics, University of California , San Francisco, California.
Kameny RJ; Department of Pediatrics, University of California , San Francisco, California.
Boehme J; Department of Pediatrics, University of California , San Francisco, California.
Gong W; Department of Pediatrics, University of California , San Francisco, California.
He Y; Department of Pediatrics, University of California , San Francisco, California.
Zhu T; Department of Pediatrics, University of California , San Francisco, California.
Maltepe E; Department of Pediatrics, University of California , San Francisco, California.
Raff GW; Department of Surgery, University of California , Davis, California.
Fineman JR; Department of Pediatrics, University of California , San Francisco, California.
Datar SA; Cardiovascular Research Institute, University of California , San Francisco, California.

Am J Physiol Heart Circ Physiol ; 315(1): H173-H181, 2018 07 01.

Article em En | MEDLINE | ID: mdl-29631374

Assuntos

Células Endoteliais/metabolismo; Fatores de Transcrição Kruppel-Like/metabolismo; Pulmão/fisiologia; Vasos Linfáticos/metabolismo; PPAR gama/metabolismo; Transdução de Sinais; Animais; Células Cultivadas; Feminino; Fatores de Transcrição Kruppel-Like/genética; Pulmão/metabolismo; Vasos Linfáticos/citologia; Vasos Linfáticos/fisiologia; Óxido Nítrico/metabolismo; PPAR gama/genética; Espécies Reativas de Oxigênio/metabolismo; Ovinos

Palavras-chave

Krüppel-like factor 2; bioavailable nitric oxide; lymphatic endothelial cell; peroxisome proliferator-activated receptor-Î³ signaling; pulmonary lymph flow

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Células Endoteliais / Vasos Linfáticos / PPAR gama / Fatores de Transcrição Kruppel-Like / Pulmão Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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