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Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types.
Finucane, Hilary K; Reshef, Yakir A; Anttila, Verneri; Slowikowski, Kamil; Gusev, Alexander; Byrnes, Andrea; Gazal, Steven; Loh, Po-Ru; Lareau, Caleb; Shoresh, Noam; Genovese, Giulio; Saunders, Arpiar; Macosko, Evan; Pollack, Samuela; Perry, John R B; Buenrostro, Jason D; Bernstein, Bradley E; Raychaudhuri, Soumya; McCarroll, Steven; Neale, Benjamin M; Price, Alkes L.
Afiliação
  • Finucane HK; Broad Institute of MIT and Harvard, Cambridge, MA, USA. finucane@broadinstitute.org.
  • Reshef YA; Department of Mathematics, Massachusetts Institute of Technology, Cambridge, MA, USA. finucane@broadinstitute.org.
  • Anttila V; Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA, USA. finucane@broadinstitute.org.
  • Slowikowski K; Department of Computer Science, Harvard University, Cambridge, MA, USA.
  • Gusev A; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Byrnes A; Analytic and Translational Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
  • Gazal S; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Loh PR; Bioinformatics and Integrative Genomics, Harvard University, Cambridge, MA, USA.
  • Lareau C; Division of Genetics, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
  • Shoresh N; Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA, USA.
  • Genovese G; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Saunders A; Analytic and Translational Genetics Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
  • Macosko E; Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA, USA.
  • Pollack S; Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA, USA.
  • Perry JRB; Department of Biostatistics, Harvard T. H. Chan School of Public Health, Boston, MA, USA.
  • Buenrostro JD; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Bernstein BE; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Raychaudhuri S; Department of Genetics, Harvard Medical School, Boston, MA, USA.
  • McCarroll S; Department of Genetics, Harvard Medical School, Boston, MA, USA.
  • Neale BM; Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA, USA.
Nat Genet ; 50(4): 621-629, 2018 04.
Article em En | MEDLINE | ID: mdl-29632380

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Expressão Gênica / Predisposição Genética para Doença Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Expressão Gênica / Predisposição Genética para Doença Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article