Lymphoblastic lymphomas in children A single-center experience from Serbia.
Srp Arh Celok Lek
; 144(7-8): 413-7, 2016.
Article
em En
| MEDLINE
| ID: mdl-29652450
ABSTRACT
Introduction:
Intensive treatment protocols used for non-Hodgkin lymphoma in children lead to eventfree survival rates ranging from 80% to 90%. However, the results are less successful in developing countries. Lymphoblastic lymphoma (LBL) is the second most frequent type of lymphoma in children, contributing with about one third to all non-Hodgkin lymphoma in childhood.Objective:
The aim of the study was to evaluate the results of LBL treatment in University Children's Hospital (UCH), Belgrade.Methods:
A retrospective analysis of patient records at UCH from 1997 to 2015 was carried out in patients aged 018 years, in whom the diagnosis of LBL had been established. Twenty-two children were included in the analysis.Results:
Mean age at diagnosis was 10 years, with preponderance of male patients. All patients were treated according to Berlin-Frankfurt-Münster-based chemotherapy protocols. With median follow-up of 91.5 months, five-year probability of event-free survival was 79.5% for all patients, while overall survival was 81.8%.Conclusion:
Our results, although slightly inferior to those of leading international groups, reflect a good treatment outcome in our patients.
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Base de dados:
MEDLINE
Assunto principal:
Leucemia-Linfoma Linfoblástico de Células Precursoras
Tipo de estudo:
Guideline
/
Observational_studies
/
Risk_factors_studies
Limite:
Adolescent
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
/
Newborn
País como assunto:
Europa
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article