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Co-amplification of EBNA-1 and PyLT through dhfr-mediated gene amplification for improving foreign protein production in transient gene expression in CHO cells.
Lee, Joo-Hyoung; Park, Jong-Ho; Park, Sun-Hye; Kim, Sun-Hong; Kim, Jee Yon; Min, Jeong-Ki; Lee, Gyun Min; Kim, Yeon-Gu.
Afiliação
  • Lee JH; Department of Biological Sciences, KAIST, 335 Gwahak-ro, Yuseong-gu, Daejeon, South Korea.
  • Park JH; Biotherapeutics Translational Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Yuseong-gu, Daejeon, South Korea.
  • Park SH; Department of Biological Sciences, KAIST, 335 Gwahak-ro, Yuseong-gu, Daejeon, South Korea.
  • Kim SH; Biotherapeutics Translational Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Yuseong-gu, Daejeon, South Korea.
  • Kim JY; Biotherapeutics Translational Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Yuseong-gu, Daejeon, South Korea.
  • Min JK; Department of Bioprocess Engineering, KRIBB School of Biotechnology, Korea University of Science and Technology (UST), 217 Gajeong-ro, Yuseong-gu, Daejeon, South Korea.
  • Lee GM; Biotherapeutics Translational Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), 125 Gwahak-ro, Yuseong-gu, Daejeon, South Korea.
  • Kim YG; Department of Life Sciences, Imperial College London, South Kensington Campus, London SW7 2AZ, UK.
Appl Microbiol Biotechnol ; 102(11): 4729-4739, 2018 Jun.
Article em En | MEDLINE | ID: mdl-29654557

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antígenos Transformantes de Poliomavirus / Amplificação de Genes / Antígenos Nucleares do Vírus Epstein-Barr / Técnicas de Amplificação de Ácido Nucleico Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antígenos Transformantes de Poliomavirus / Amplificação de Genes / Antígenos Nucleares do Vírus Epstein-Barr / Técnicas de Amplificação de Ácido Nucleico Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article