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Phase III randomized study of second line ADI-PEG 20 plus best supportive care versus placebo plus best supportive care in patients with advanced hepatocellular carcinoma.
Abou-Alfa, G K; Qin, S; Ryoo, B-Y; Lu, S-N; Yen, C-J; Feng, Y-H; Lim, H Y; Izzo, F; Colombo, M; Sarker, D; Bolondi, L; Vaccaro, G; Harris, W P; Chen, Z; Hubner, R A; Meyer, T; Sun, W; Harding, J J; Hollywood, E M; Ma, J; Wan, P J; Ly, M; Bomalaski, J; Johnston, A; Lin, C-C; Chao, Y; Chen, L-T.
Afiliação
  • Abou-Alfa GK; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, USA; Department of Medicine, Weill Cornell Medical College, New York, USA. Electronic address: abou-alg@mskcc.org.
  • Qin S; Department of Oncology, The Chinese People's Liberation Army 81 Hospital, Nanjing, China.
  • Ryoo BY; Department of Oncology, Asan Medical Center, Seoul, South Korea.
  • Lu SN; Department of Medical Oncology, Kaohsiung Chang Gung Memorial Hospital, Taiwan; Chang Gung University College of Medicine, Taiwan.
  • Yen CJ; Department of Oncology, National Cheng Kung University Hospital, Taiwan.
  • Feng YH; Department of Oncology, Chi Mei Medical Center-Yong Kang, Taiwan.
  • Lim HY; Department of Medical Oncology, Samsung Medical Center, Seoul, South Korea.
  • Izzo F; Department of Medicine, Fondazione Giovanni Pascale, Napoli.
  • Colombo M; Department of Medicine, Fondazione IRCCS Ca, Milan, Italy.
  • Sarker D; Department of Medicine, King's College Hospital, London, UK.
  • Bolondi L; Department of Medicine, Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
  • Vaccaro G; Department of Medicine, Oregon Health Sciences University, Portland.
  • Harris WP; Department of Medicine, University of Washington Medical Center, Seattle, USA.
  • Chen Z; Department of Oncology, 2nd Hospital of Anhui Medical University, Hefei, China.
  • Hubner RA; Department of Medicine, The Christie NHS Foundation Trust, Manchester, UK.
  • Meyer T; Department of Medicine, Royal Free Hospital and UCL Cancer Institute, London, UK.
  • Sun W; Department of Medicine, University of Pittsburgh, Pittsburgh, USA.
  • Harding JJ; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, USA; Department of Medicine, Weill Cornell Medical College, New York, USA.
  • Hollywood EM; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, USA.
  • Ma J; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, USA.
  • Wan PJ; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, USA.
  • Ly M; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, USA.
  • Bomalaski J; Department of Research and Development, Polaris Pharmaceuticals, Inc., San Diego, USA.
  • Johnston A; Department of Research and Development, Polaris Pharmaceuticals, Inc., San Diego, USA.
  • Lin CC; Department of Medical Oncology, Chang Gung Medical Foundation LK, Taipei, Tainan.
  • Chao Y; Department of Medicine, Veterans General Hospital-Taipei, Taipei, Tainan.
  • Chen LT; Chang Gung University College of Medicine, Taiwan; Department of Medical Oncology, National Institute of Cancer Research, National Health Research Institutes, Tainan; Department of Oncology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.
Ann Oncol ; 29(6): 1402-1408, 2018 06 01.
Article em En | MEDLINE | ID: mdl-29659672
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cuidados Paliativos / Polietilenoglicóis / Carcinoma Hepatocelular / Hidrolases / Neoplasias Hepáticas Tipo de estudo: Clinical_trials / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cuidados Paliativos / Polietilenoglicóis / Carcinoma Hepatocelular / Hidrolases / Neoplasias Hepáticas Tipo de estudo: Clinical_trials / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2018 Tipo de documento: Article