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Yangonin protects against cholestasis and hepatotoxity via activation of farnesoid X receptor in vivo and in vitro.
Gao, Xiaoguang; Fu, Ting; Wang, Changyuan; Ning, Chenqing; Liu, Kexin; Liu, Zhihao; Sun, Huijun; Ma, Xiaodong; Huo, Xiaokui; Yang, Xiaobo; Zou, Ming; Meng, Qiang.
Afiliação
  • Gao X; Department of Clinical Pharmacology, College of Pharmacy, Dalian Medical University, Dalian 116044, China.
  • Fu T; Pharmacy Department of Affiliated Zhongshan Hospital of Dalian University, Dalian, China.
  • Wang C; Department of Clinical Pharmacology, College of Pharmacy, Dalian Medical University, Dalian 116044, China; Key Laboratory of Pharmacokinetics and Transport of Liaoning Province, Dalian Medical University, Dalian 116044, China.
  • Ning C; Department of Clinical Pharmacology, College of Pharmacy, Dalian Medical University, Dalian 116044, China.
  • Liu K; Department of Clinical Pharmacology, College of Pharmacy, Dalian Medical University, Dalian 116044, China; Key Laboratory of Pharmacokinetics and Transport of Liaoning Province, Dalian Medical University, Dalian 116044, China.
  • Liu Z; Department of Clinical Pharmacology, College of Pharmacy, Dalian Medical University, Dalian 116044, China; Key Laboratory of Pharmacokinetics and Transport of Liaoning Province, Dalian Medical University, Dalian 116044, China.
  • Sun H; Department of Clinical Pharmacology, College of Pharmacy, Dalian Medical University, Dalian 116044, China; Key Laboratory of Pharmacokinetics and Transport of Liaoning Province, Dalian Medical University, Dalian 116044, China.
  • Ma X; Department of Clinical Pharmacology, College of Pharmacy, Dalian Medical University, Dalian 116044, China; Key Laboratory of Pharmacokinetics and Transport of Liaoning Province, Dalian Medical University, Dalian 116044, China.
  • Huo X; Department of Clinical Pharmacology, College of Pharmacy, Dalian Medical University, Dalian 116044, China.
  • Yang X; Department of Clinical Pharmacology, College of Pharmacy, Dalian Medical University, Dalian 116044, China; Key Laboratory of Pharmacokinetics and Transport of Liaoning Province, Dalian Medical University, Dalian 116044, China.
  • Zou M; Pharmacy Department of Affiliated Zhongshan Hospital of Dalian University, Dalian, China.
  • Meng Q; Department of Clinical Pharmacology, College of Pharmacy, Dalian Medical University, Dalian 116044, China; Key Laboratory of Pharmacokinetics and Transport of Liaoning Province, Dalian Medical University, Dalian 116044, China. Electronic address: qiangmeng@dlmedu.edu.cn.
Toxicol Appl Pharmacol ; 348: 105-116, 2018 06 01.
Article em En | MEDLINE | ID: mdl-29660435
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pironas / Colestase / Receptores Citoplasmáticos e Nucleares / Substâncias Protetoras / Doença Hepática Induzida por Substâncias e Drogas / Fígado Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pironas / Colestase / Receptores Citoplasmáticos e Nucleares / Substâncias Protetoras / Doença Hepática Induzida por Substâncias e Drogas / Fígado Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2018 Tipo de documento: Article