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Tranilast inhibits the expression of genes related to epithelial-mesenchymal transition and angiogenesis in neurofibromin-deficient cells.
Harigai, Ritsuko; Sakai, Shigeki; Nobusue, Hiroyuki; Hirose, Chikako; Sampetrean, Oltea; Minami, Noriaki; Hata, Yukie; Kasama, Takashi; Hirose, Takanori; Takenouchi, Toshiki; Kosaki, Kenjiro; Kishi, Kazuo; Saya, Hideyuki; Arima, Yoshimi.
Afiliação
  • Harigai R; Division of Gene Regulation, Institute for Advanced Medical Research, Keio University School of Medicine, Tokyo, 160-8582, Japan.
  • Sakai S; Department of Plastic and Reconstructive Surgery, Keio University School of Medicine, Tokyo, 160-8582, Japan.
  • Nobusue H; Division of Gene Regulation, Institute for Advanced Medical Research, Keio University School of Medicine, Tokyo, 160-8582, Japan.
  • Hirose C; Division of Gene Regulation, Institute for Advanced Medical Research, Keio University School of Medicine, Tokyo, 160-8582, Japan.
  • Sampetrean O; Department of Surgery, Keio University School of Medicine, Tokyo, 160-8582, Japan.
  • Minami N; Division of Gene Regulation, Institute for Advanced Medical Research, Keio University School of Medicine, Tokyo, 160-8582, Japan.
  • Hata Y; Division of Gene Regulation, Institute for Advanced Medical Research, Keio University School of Medicine, Tokyo, 160-8582, Japan.
  • Kasama T; Department of Neurosurgery, Kobe University Graduate School of Medicine, Hyogo, 650-0017, Japan.
  • Hirose T; Department of Biomedical Research & Development, Link Genomics Inc, Tokyo, 103-0024, Japan.
  • Takenouchi T; Department of Biomedical Research & Development, Link Genomics Inc, Tokyo, 103-0024, Japan.
  • Kosaki K; Department of Pathology for Regional Communication, Kobe University Graduate School of Medicine, Hyogo, 650-0017, Japan.
  • Kishi K; Department of Paediatrics, Keio University School of Medicine, Tokyo, 160-8582, Japan.
  • Saya H; Center for Medical Genetics, Keio University School of Medicine, Tokyo, 160-8582, Japan.
  • Arima Y; Department of Plastic and Reconstructive Surgery, Keio University School of Medicine, Tokyo, 160-8582, Japan.
Sci Rep ; 8(1): 6069, 2018 04 17.
Article em En | MEDLINE | ID: mdl-29666462
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neovascularização Fisiológica / Antialérgicos / Neurofibromina 1 / Transição Epitelial-Mesenquimal / Ortoaminobenzoatos Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neovascularização Fisiológica / Antialérgicos / Neurofibromina 1 / Transição Epitelial-Mesenquimal / Ortoaminobenzoatos Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article