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Synthesis and biological evaluation of aryl-oxadiazoles as inhibitors of Mycobacterium tuberculosis.
Martinez-Grau, Maria Angeles; Valcarcel, Isabel C Gonzalez; Early, Julie V; Gessner, Richard Klaus; de Melo, Candice Soares; de la Nava, Eva Maria Martin; Korkegian, Aaron; Ovechkina, Yulia; Flint, Lindsay; Gravelle, Anisa; Cramer, Jeff W; Desai, Prashant V; Street, Leslie J; Odingo, Joshua; Masquelin, Thierry; Chibale, Kelly; Parish, Tanya.
Afiliação
  • Martinez-Grau MA; Lilly Research Laboratories, Eli Lilly and Company, Avda. de la Industria 30, 28108-Alcobendas, Madrid, Spain.
  • Valcarcel ICG; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, USA.
  • Early JV; TB Discovery Research, Infectious Disease Research Institute, 1616 Eastlake Ave E, Suite 400, Seattle, WA 98102, United States.
  • Gessner RK; Drug Discovery and Development Centre (H3D), Department of Chemistry, University of Cape Town, Rondebosch 7701, South Africa; South African Medical Research Council Drug Discovery and Development Research Unit, Department of Chemistry, University of Cape Town, Rondebosch 7701, South Africa; Institut
  • de Melo CS; Drug Discovery and Development Centre (H3D), Department of Chemistry, University of Cape Town, Rondebosch 7701, South Africa; South African Medical Research Council Drug Discovery and Development Research Unit, Department of Chemistry, University of Cape Town, Rondebosch 7701, South Africa; Institut
  • de la Nava EMM; Lilly Research Laboratories, Eli Lilly and Company, Avda. de la Industria 30, 28108-Alcobendas, Madrid, Spain.
  • Korkegian A; TB Discovery Research, Infectious Disease Research Institute, 1616 Eastlake Ave E, Suite 400, Seattle, WA 98102, United States.
  • Ovechkina Y; TB Discovery Research, Infectious Disease Research Institute, 1616 Eastlake Ave E, Suite 400, Seattle, WA 98102, United States.
  • Flint L; TB Discovery Research, Infectious Disease Research Institute, 1616 Eastlake Ave E, Suite 400, Seattle, WA 98102, United States.
  • Gravelle A; TB Discovery Research, Infectious Disease Research Institute, 1616 Eastlake Ave E, Suite 400, Seattle, WA 98102, United States.
  • Cramer JW; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, USA.
  • Desai PV; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, USA.
  • Street LJ; Drug Discovery and Development Centre (H3D), Department of Chemistry, University of Cape Town, Rondebosch 7701, South Africa; South African Medical Research Council Drug Discovery and Development Research Unit, Department of Chemistry, University of Cape Town, Rondebosch 7701, South Africa; Institut
  • Odingo J; TB Discovery Research, Infectious Disease Research Institute, 1616 Eastlake Ave E, Suite 400, Seattle, WA 98102, United States.
  • Masquelin T; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, IN 46285, USA.
  • Chibale K; Drug Discovery and Development Centre (H3D), Department of Chemistry, University of Cape Town, Rondebosch 7701, South Africa; South African Medical Research Council Drug Discovery and Development Research Unit, Department of Chemistry, University of Cape Town, Rondebosch 7701, South Africa; Institut
  • Parish T; TB Discovery Research, Infectious Disease Research Institute, 1616 Eastlake Ave E, Suite 400, Seattle, WA 98102, United States. Electronic address: tanya.parish@idri.org.
Bioorg Med Chem Lett ; 28(10): 1758-1764, 2018 06 01.
Article em En | MEDLINE | ID: mdl-29680666
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oxidiazóis / Antibacterianos / Mycobacterium tuberculosis Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oxidiazóis / Antibacterianos / Mycobacterium tuberculosis Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2018 Tipo de documento: Article