Successful Treatment of Cerebral Toxoplasmosis Using Pyrimethamine Oral Solution Compounded From Inexpensive Bulk Powder.

Hodgson, Hayley A; Sim, Taeyong; Gonzalez, Hemil; Aziz, Mariam; Rhee, Yoona; Lewis, Paul O; Jhobalia, Neel; Shields, Beth; Wang, Sheila K.

Afiliação

Hodgson HA; Midwestern University Chicago College of Pharmacy, Downers Grove, Illinois.
Sim T; Department of Pharmacy, Department of Internal Medicine, Chicago, Illinois.
Gonzalez H; Division of Infectious Diseases, Department of Internal Medicine, Chicago, Illinois.
Aziz M; Division of Infectious Diseases, Department of Internal Medicine, Chicago, Illinois.
Rhee Y; Division of Infectious Diseases, Department of Internal Medicine, Chicago, Illinois.
Lewis PO; Division of Infectious Diseases, Department of Internal Medicine, Chicago, Illinois.
Jhobalia N; Department of Pharmacy, Johnson City Medical Center, Johnson City, Tennessee.
Shields B; Rush Specialty Drug Solutions, Rush University Medical Center, Chicago, Illinois.
Wang SK; Department of Pharmacy, Department of Internal Medicine, Chicago, Illinois.

Open Forum Infect Dis ; 5(4): ofy055, 2018 Apr.

Article em En | MEDLINE | ID: mdl-29693038

ABSTRACT

A price increase of pyrimethamine tablets in the United States has made the life-saving drug difficult to acquire for hospitalized patients who need it most. We report the successful use of a pyrimethamine oral suspension compounded from an economical bulk powder in a patient with acute toxoplasmic encephalitis.

Palavras-chave

Toxoplasma gondii; bulk powder; encephalitis; oral suspension; pyrimethamine

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2018 Tipo de documento: Article