Spontaneous regression of primary cutaneous diffuse large B-cell lymphoma, leg type with significant T-cell immune response.
JAAD Case Rep
; 4(4): 305-309, 2018 May.
Article
em En
| MEDLINE
| ID: mdl-29693055
ABSTRACT
We report a case of histologically confirmed primary cutaneous diffuse large B-cell lymphoma, leg type (PCDLBCL-LT) that subsequently underwent spontaneous regression in the absence of systemic treatment. The case showed an atypical lymphoid infiltrate that was CD20+ and MUM-1+ and CD10-. A subsequent biopsy of the spontaneously regressed lesion showed fibrosis associated with a lymphocytic infiltrate comprising reactive T cells. PCDLBCL-LT is a cutaneous B-cell lymphoma with a poor prognosis, which is usually treated with chemotherapy. We describe a case of clinical and histologic spontaneous regression in a patient with PCDLBCL-LT who had a negative systemic workup but a recurrence over a year after his initial presentation.
B cell; PCDLBCL-LT, primary cutaneous diffuse large B-cell lymphoma, leg type; PCDLBCL-other, primary cutaneous diffuse large B-cell lymphoma, other; PCFCL, primary cutaneous follicle center lymphoma; PCMZL, primary cutaneous marginal zone lymphoma; R-CHOP, rituximab, cyclophosphamide, doxorubicin, oncovin/vincristine, and prednisone; leg type; lymphoma; primary cutaneous diffuse large B-cell lymphoma; regression
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Base de dados:
MEDLINE
Tipo de estudo:
Prognostic_studies
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article