Curdlan sulfate-<i>O</i>-linked quaternized chitosan nanoparticles: potential adjuvants to improve the immunogenicity of exogenous antigens via intranasal vaccination.

Zhang, Shu; Huang, Shengshi; Lu, Lu; Song, Xinlei; Li, Pingli; Wang, Fengshan

Curdlan sulfate-O-linked quaternized chitosan nanoparticles: potential adjuvants to improve the immunogenicity of exogenous antigens via intranasal vaccination.

Zhang, Shu; Huang, Shengshi; Lu, Lu; Song, Xinlei; Li, Pingli; Wang, Fengshan.

Afiliação

Zhang S; Key Laboratory of Chemical Biology of Natural Products (Ministry of Education), Institute of Biochemical and Biotechnological Drugs, School of Pharmaceutical Sciences, Shandong University, Jinan, Shandong.
Huang S; National Glycoengineering Research Center, Shandong Provincial Key Laboratory of Carbohydrate Chemistry and Glycobiology, Shandong University, Jinan, Shandong.
Lu L; Key Laboratory of Chemical Biology of Natural Products (Ministry of Education), Institute of Biochemical and Biotechnological Drugs, School of Pharmaceutical Sciences, Shandong University, Jinan, Shandong.
Song X; Key Laboratory of Chemical Biology of Natural Products (Ministry of Education), Institute of Biochemical and Biotechnological Drugs, School of Pharmaceutical Sciences, Shandong University, Jinan, Shandong.
Li P; Institute of Clinical Pharmacology, Qilu Hospital of Shandong University, Jinan, Shandong, China.
Wang F; Key Laboratory of Chemical Biology of Natural Products (Ministry of Education), Institute of Biochemical and Biotechnological Drugs, School of Pharmaceutical Sciences, Shandong University, Jinan, Shandong.

Int J Nanomedicine ; 13: 2377-2394, 2018.

Article em En | MEDLINE | ID: mdl-29713168

Assuntos

Adjuvantes Imunológicos/administração & dosagem; Antígenos/administração & dosagem; Quitosana/química; Nanopartículas/administração & dosagem; beta-Glucanas/química; Administração Intranasal; Animais; Antígenos/imunologia; Proliferação de Células/efeitos dos fármacos; Quitosana/imunologia; Feminino; Imunidade nas Mucosas; Imunização; Linfócitos/efeitos dos fármacos; Linfócitos/imunologia; Camundongos Endogâmicos BALB C; Nanopartículas/química; Líquido da Lavagem Nasal/imunologia; Ovalbumina/administração & dosagem; Ovalbumina/imunologia

Palavras-chave

O-linked quaternized chitosan; adjuvant; curdlan sulfate; immune response; nanoparticle; nasal mucosa immunization; ovalbumin

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Adjuvantes Imunológicos / Quitosana / Beta-Glucanas / Nanopartículas / Antígenos Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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