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Phosphodiesterase 4 and 7 inhibitors produce protective effects against high glucose-induced neurotoxicity in PC12 cells via modulation of the oxidative stress, apoptosis and inflammation pathways.
Namazi Sarvestani, Nazanin; Saberi Firouzi, Saeedeh; Falak, Reza; Karimi, Mohammad Yahya; Davoodzadeh Gholami, Mohammad; Rangbar, Akram; Hosseini, Asieh.
Afiliação
  • Namazi Sarvestani N; Department of Animal Biology, School of Biology, Department of Science, University of Tehran, Tehran, Iran.
  • Saberi Firouzi S; Department of Pharmacology, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
  • Falak R; Department of Immunology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
  • Karimi MY; Razi Drug Research Center, Iran University of Medical Sciences, Tehran, Iran.
  • Davoodzadeh Gholami M; Department of Immunology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
  • Rangbar A; Department of Toxicology and Pharmacology, School of Pharmacy, Hamadan University of Medical Sciences, Hamadan, Iran.
  • Hosseini A; Razi Drug Research Center, Iran University of Medical Sciences, Tehran, Iran. hoseini.as@iums.ac.ir.
Metab Brain Dis ; 33(4): 1293-1306, 2018 08.
Article em En | MEDLINE | ID: mdl-29713919
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores de Fosfodiesterase / Apoptose / Estresse Oxidativo / Fármacos Neuroprotetores / Glucose / Inflamação Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Inibidores de Fosfodiesterase / Apoptose / Estresse Oxidativo / Fármacos Neuroprotetores / Glucose / Inflamação Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article