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Pharmacological characterization of potent and selective NaV1.7 inhibitors engineered from Chilobrachys jingzhao tarantula venom peptide JzTx-V.
Moyer, Bryan D; Murray, Justin K; Ligutti, Joseph; Andrews, Kristin; Favreau, Philippe; Jordan, John B; Lee, Josie H; Liu, Dong; Long, Jason; Sham, Kelvin; Shi, Licheng; Stöcklin, Reto; Wu, Bin; Yin, Ruoyuan; Yu, Violeta; Zou, Anruo; Biswas, Kaustav; Miranda, Les P.
Afiliação
  • Moyer BD; Neuroscience, Amgen Discovery Research, Thousand Oaks, California, United States of America.
  • Murray JK; Therapeutic Discovery, Amgen Discovery Research, Thousand Oaks, California, United States of America.
  • Ligutti J; Neuroscience, Amgen Discovery Research, Thousand Oaks, California, United States of America.
  • Andrews K; Molecular Engineering, Amgen Discovery Research, Cambridge, Massachusetts, United States of America.
  • Favreau P; Atheris Laboratories, CH Bernex, Geneva, Switzerland.
  • Jordan JB; Discovery Attribute Sciences, Amgen Discovery Research, Thousand Oaks, California, United States of America.
  • Lee JH; Neuroscience, Amgen Discovery Research, Cambridge, Massachusetts, United States of America.
  • Liu D; Neuroscience, Amgen Discovery Research, Thousand Oaks, California, United States of America.
  • Long J; Therapeutic Discovery, Amgen Discovery Research, Thousand Oaks, California, United States of America.
  • Sham K; Therapeutic Discovery, Amgen Discovery Research, Thousand Oaks, California, United States of America.
  • Shi L; Neuroscience, Amgen Discovery Research, Thousand Oaks, California, United States of America.
  • Stöcklin R; Atheris Laboratories, CH Bernex, Geneva, Switzerland.
  • Wu B; Therapeutic Discovery, Amgen Discovery Research, Thousand Oaks, California, United States of America.
  • Yin R; Neuroscience, Amgen Discovery Research, Thousand Oaks, California, United States of America.
  • Yu V; Neuroscience, Amgen Discovery Research, Cambridge, Massachusetts, United States of America.
  • Zou A; Neuroscience, Amgen Discovery Research, Thousand Oaks, California, United States of America.
  • Biswas K; Therapeutic Discovery, Amgen Discovery Research, Thousand Oaks, California, United States of America.
  • Miranda LP; Therapeutic Discovery, Amgen Discovery Research, Thousand Oaks, California, United States of America.
PLoS One ; 13(5): e0196791, 2018.
Article em En | MEDLINE | ID: mdl-29723257
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeos / Venenos de Aranha / Bloqueadores dos Canais de Sódio / Canal de Sódio Disparado por Voltagem NAV1.7 / Analgésicos Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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XML
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Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Peptídeos / Venenos de Aranha / Bloqueadores dos Canais de Sódio / Canal de Sódio Disparado por Voltagem NAV1.7 / Analgésicos Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2018 Tipo de documento: Article