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Effect of an siRNA Therapeutic Targeting PCSK9 on Atherogenic Lipoproteins: Prespecified Secondary End Points in ORION 1.
Ray, Kausik K; Stoekenbroek, Robert M; Kallend, David; Leiter, Lawrence A; Landmesser, Ulf; Wright, R Scott; Wijngaard, Peter; Kastelein, John J P.
Afiliação
  • Ray KK; Imperial Centre for Cardiovascular Disease Prevention, Department of Primary Care and Public Health, Imperial College London, UK (K.K.R.).
  • Stoekenbroek RM; Department of Vascular Medicine, Academic Medical Center, University of Amsterdam, the Netherlands (R.M.S., J.J.P.K.).
  • Kallend D; The Medicines Company, Parsippany, NJ (D.K., P.W.).
  • Leiter LA; Division of Endocrinology and Metabolism, Li Ka Shing Knowledge Institute, St. Michael's Hospital, University of Toronto, Canada (L.A.L.).
  • Landmesser U; Department of Cardiology, Charité-Universitätsmedizin Berlin, Berlin Institute of Health and German Center for Cardiovascular Research, Partner Site Berlin, Germany (U.L.).
  • Wright RS; Department of Cardiology, Mayo Clinic, Rochester, MN (R.S.W.).
  • Wijngaard P; The Medicines Company, Parsippany, NJ (D.K., P.W.).
  • Kastelein JJP; Department of Vascular Medicine, Academic Medical Center, University of Amsterdam, the Netherlands (R.M.S., J.J.P.K.).
Circulation ; 138(13): 1304-1316, 2018 09 25.
Article em En | MEDLINE | ID: mdl-29735484

Texto completo: 1 Base de dados: MEDLINE Assunto principal: RNA Interferente Pequeno / Dislipidemias / Terapêutica com RNAi / Pró-Proteína Convertase 9 / Lipídeos Tipo de estudo: Clinical_trials / Diagnostic_studies / Guideline / Prognostic_studies Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: RNA Interferente Pequeno / Dislipidemias / Terapêutica com RNAi / Pró-Proteína Convertase 9 / Lipídeos Tipo de estudo: Clinical_trials / Diagnostic_studies / Guideline / Prognostic_studies Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2018 Tipo de documento: Article