Control of mitochondrial superoxide production by reverse electron transport at complex I.

Robb, Ellen L; Hall, Andrew R; Prime, Tracy A; Eaton, Simon; Szibor, Marten; Viscomi, Carlo; James, Andrew M; Murphy, Michael P

Robb, Ellen L; Hall, Andrew R; Prime, Tracy A; Eaton, Simon; Szibor, Marten; Viscomi, Carlo; James, Andrew M; Murphy, Michael P.

Afiliação

Robb EL; From the Medical Research Council Mitochondrial Biology Unit, Hills Road, University of Cambridge, Cambridge CB2 0XY, United Kingdom.
Hall AR; From the Medical Research Council Mitochondrial Biology Unit, Hills Road, University of Cambridge, Cambridge CB2 0XY, United Kingdom.
Prime TA; From the Medical Research Council Mitochondrial Biology Unit, Hills Road, University of Cambridge, Cambridge CB2 0XY, United Kingdom.
Eaton S; the UCL Great Ormond Street Institute of Child Health, London WC1N 1EH, United Kingdom.
Szibor M; the Faculty of Medicine and Life Sciences, University of Tampere, Tampere FI-33014, Finland, and.
Viscomi C; the Max-Planck-Institute for Heart and Lung Research, Ludwigstrasse 43, 61231 Bad Nauheim, Germany.
James AM; From the Medical Research Council Mitochondrial Biology Unit, Hills Road, University of Cambridge, Cambridge CB2 0XY, United Kingdom.
Murphy MP; From the Medical Research Council Mitochondrial Biology Unit, Hills Road, University of Cambridge, Cambridge CB2 0XY, United Kingdom.

J Biol Chem ; 293(25): 9869-9879, 2018 06 22.

Article em En | MEDLINE | ID: mdl-29743240

Assuntos

Complexo I de Transporte de Elétrons/metabolismo; Peróxido de Hidrogênio/metabolismo; Mitocôndrias Cardíacas/metabolismo; Superóxidos/metabolismo; Ubiquinona/metabolismo; Animais; Transporte de Elétrons; Feminino; Masculino; Camundongos; Camundongos Endogâmicos C57BL; Fosforilação Oxidativa; Ratos; Ratos Wistar; Transdução de Sinais

Palavras-chave

RET; coenzyme Q; complex I; mitochondria; mitochondrial membrane potential; reactive oxygen species (ROS); redox signaling; respiration; reverse electron transport; superoxide

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ubiquinona / Superóxidos / Complexo I de Transporte de Elétrons / Peróxido de Hidrogênio / Mitocôndrias Cardíacas Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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