Reference-less MR thermometry on pre-clinical thiel human cadaver for liver surgery with MRgFUS.
Minim Invasive Ther Allied Technol
; 28(1): 15-21, 2019 Feb.
Article
em En
| MEDLINE
| ID: mdl-29764258
ABSTRACT
PURPOSE:
Reference-less MR thermometry can be a promising technique for temperature mapping during liver treatment with Magnetic Resonance-guided Focused Ultrasound (MRgFUS), as it is more robust to breathing motion than Proton Resonance Frequency MR thermometry. However, there is a lack of a pre-clinical model for repeatable testing of reference-less thermometry. The purpose of this work was to verify the explanted Thiel embalmed human liver and whole Thiel embalmed human cadaver for application of a custom made reference-less thermometry algorithm during MRgFUS sonication. MATERIAL ANDMETHODS:
Phase maps were generated during sonication as an input to the algorithm. A square Region-of-Interest (ROI) was designed around the heated area. The ROI was interpolated using a two-dimensional polynomial to the surrounding phase map to calculate the background phase.RESULTS:
Using the phase information from the images, the temperature rise was measured. Validation of the methodology showed accordance of temperatures with actual temperatures.CONCLUSIONS:
The explanted liver and the whole cadaver constitute a promising and feasible model to study reference-less techniques for thermometry during MRgFUS, before clinical trials.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Imageamento por Ressonância Magnética
/
Termometria
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Fígado
Limite:
Humans
Idioma:
En
Ano de publicação:
2019
Tipo de documento:
Article