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Investigations on small molecule inhibitors targeting the histone H3K4 tri-methyllysine binding PHD-finger of JmjC histone demethylases.
Bhushan, Bhaskar; Erdmann, Alexandre; Zhang, Yijia; Belle, Roman; Johannson, Catrine; Oppermann, Udo; Hopkinson, Richard J; Schofield, Christopher J; Kawamura, Akane.
Afiliação
  • Bhushan B; Department of Chemistry, University of Oxford, Mansfield Road, Oxford OX1 3TA, United Kingdom; Radcliffe Department of Medicine, Division of Cardiovascular Medicine, University of Oxford, The Wellcome Trust Centre for Human Genetics, Roosevelt Drive, Oxford OX3 7BN, United Kingdom.
  • Erdmann A; Department of Chemistry, University of Oxford, Mansfield Road, Oxford OX1 3TA, United Kingdom.
  • Zhang Y; Department of Chemistry, University of Oxford, Mansfield Road, Oxford OX1 3TA, United Kingdom.
  • Belle R; Department of Chemistry, University of Oxford, Mansfield Road, Oxford OX1 3TA, United Kingdom.
  • Johannson C; Department of Chemistry, University of Oxford, Mansfield Road, Oxford OX1 3TA, United Kingdom; Botnar Research Centre, NIHR Oxford Biomedical Research Unit, University of Oxford, Oxford, United Kingdom.
  • Oppermann U; Botnar Research Centre, NIHR Oxford Biomedical Research Unit, University of Oxford, Oxford, United Kingdom.
  • Hopkinson RJ; Department of Chemistry, University of Oxford, Mansfield Road, Oxford OX1 3TA, United Kingdom.
  • Schofield CJ; Department of Chemistry, University of Oxford, Mansfield Road, Oxford OX1 3TA, United Kingdom.
  • Kawamura A; Department of Chemistry, University of Oxford, Mansfield Road, Oxford OX1 3TA, United Kingdom; Radcliffe Department of Medicine, Division of Cardiovascular Medicine, University of Oxford, The Wellcome Trust Centre for Human Genetics, Roosevelt Drive, Oxford OX3 7BN, United Kingdom. Electronic addres
Bioorg Med Chem ; 26(11): 2984-2991, 2018 07 15.
Article em En | MEDLINE | ID: mdl-29764755
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Histonas / Sistemas de Liberação de Medicamentos / Bibliotecas de Moléculas Pequenas / Histona Desmetilases Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Histonas / Sistemas de Liberação de Medicamentos / Bibliotecas de Moléculas Pequenas / Histona Desmetilases Idioma: En Ano de publicação: 2018 Tipo de documento: Article