An epizootic of Chlamydia psittaci equine reproductive loss associated with suspected spillover from native Australian parrots.
Emerg Microbes Infect
; 7(1): 88, 2018 May 16.
Article
em En
| MEDLINE
| ID: mdl-29765033
ABSTRACT
Chlamydia psittaci is an avian pathogen capable of spill-over infections to humans. A parrot C. psittaci strain was recently detected in an equine reproductive loss case associated with a subsequent cluster of human C. psittaci infections. In this study, we screened for C. psittaci in cases of equine reproductive loss reported in regional New South Wales, Australia during the 2016 foaling season. C. psittaci specific-PCR screening of foetal and placental tissue samples from cases of equine abortion (n = 161) and foals with compromised health status (n = 38) revealed C. psittaci positivity of 21.1% and 23.7%, respectively. There was a statistically significant geographical clustering of cases ~170 km inland from the mid-coast of NSW (P < 0.001). Genomic analysis and molecular typing of C. psittaci positive samples from this study and the previous Australian equine index case revealed that the equine strains from different studs in regional NSW were clonal, while the phylogenetic analysis revealed that the C. psittaci strains from both Australian equine disease clusters belong to the parrot-associated 6BC clade, again indicative of spill-over of C. psittaci infections from native Australian parrots. The results of this work suggest that C. psittaci may be a more significant agent of equine reproductive loss than thought. A range of studies are now required to evaluate (a) the exact role that C. psittaci plays in equine reproductive loss; (b) the range of potential avian reservoirs and factors influencing infection spill-over; and
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Psitacose
/
Placenta
/
Complicações Infecciosas na Gravidez
/
Chlamydophila psittaci
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Feto Abortado
/
Doenças dos Cavalos
Tipo de estudo:
Risk_factors_studies
Limite:
Animals
/
Pregnancy
País como assunto:
Oceania
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article