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RNP-Granule Assembly via Ataxin-2 Disordered Domains Is Required for Long-Term Memory and Neurodegeneration.
Bakthavachalu, Baskar; Huelsmeier, Joern; Sudhakaran, Indulekha P; Hillebrand, Jens; Singh, Amanjot; Petrauskas, Arnas; Thiagarajan, Devasena; Sankaranarayanan, M; Mizoue, Laura; Anderson, Eric N; Pandey, Udai Bhan; Ross, Eric; VijayRaghavan, K; Parker, Roy; Ramaswami, Mani.
Afiliação
  • Bakthavachalu B; National Centre for Biological Sciences, TIFR, Bangalore 560065, India.
  • Huelsmeier J; Trinity College Institute of Neuroscience, School of Genetics and Microbiology, Smurfit Institute of Genetics and School of Natural Sciences, Trinity College Dublin, Dublin-2, Ireland.
  • Sudhakaran IP; National Centre for Biological Sciences, TIFR, Bangalore 560065, India.
  • Hillebrand J; Trinity College Institute of Neuroscience, School of Genetics and Microbiology, Smurfit Institute of Genetics and School of Natural Sciences, Trinity College Dublin, Dublin-2, Ireland.
  • Singh A; National Centre for Biological Sciences, TIFR, Bangalore 560065, India.
  • Petrauskas A; Trinity College Institute of Neuroscience, School of Genetics and Microbiology, Smurfit Institute of Genetics and School of Natural Sciences, Trinity College Dublin, Dublin-2, Ireland.
  • Thiagarajan D; National Centre for Biological Sciences, TIFR, Bangalore 560065, India.
  • Sankaranarayanan M; National Centre for Biological Sciences, TIFR, Bangalore 560065, India.
  • Mizoue L; Department of Chemistry, University of Colorado, Boulder, CO 80309, USA; HHMI, University of Colorado, Boulder, CO 80309, USA.
  • Anderson EN; Department of Pediatrics, Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.
  • Pandey UB; Department of Pediatrics, Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.
  • Ross E; Department of Biochemistry and Molecular Biology, Colorado State University, Fort Collins, CO 80523, USA.
  • VijayRaghavan K; National Centre for Biological Sciences, TIFR, Bangalore 560065, India.
  • Parker R; Department of Chemistry, University of Colorado, Boulder, CO 80309, USA; HHMI, University of Colorado, Boulder, CO 80309, USA.
  • Ramaswami M; National Centre for Biological Sciences, TIFR, Bangalore 560065, India; Trinity College Institute of Neuroscience, School of Genetics and Microbiology, Smurfit Institute of Genetics and School of Natural Sciences, Trinity College Dublin, Dublin-2, Ireland. Electronic address: mani.ramaswami@tcd.ie.
Neuron ; 98(4): 754-766.e4, 2018 05 16.
Article em En | MEDLINE | ID: mdl-29772202
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ribonucleoproteínas / Doenças Neurodegenerativas / Grânulos Citoplasmáticos / Proteínas de Drosophila / Memória de Longo Prazo / Proteínas Intrinsicamente Desordenadas / Ataxina-2 Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ribonucleoproteínas / Doenças Neurodegenerativas / Grânulos Citoplasmáticos / Proteínas de Drosophila / Memória de Longo Prazo / Proteínas Intrinsicamente Desordenadas / Ataxina-2 Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article