SRC-3 Coactivator Governs Dynamic Estrogen-Induced Chromatin Looping Interactions during Transcription.

Panigrahi, Anil K; Foulds, Charles E; Lanz, Rainer B; Hamilton, Ross A; Yi, Ping; Lonard, David M; Tsai, Ming-Jer; Tsai, Sophia Y; O'Malley, Bert W

Panigrahi, Anil K; Foulds, Charles E; Lanz, Rainer B; Hamilton, Ross A; Yi, Ping; Lonard, David M; Tsai, Ming-Jer; Tsai, Sophia Y; O'Malley, Bert W.

Afiliação

Panigrahi AK; Department of Molecular and Cellular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.
Foulds CE; Department of Molecular and Cellular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA; Center for Precision Environmental Health, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.
Lanz RB; Department of Molecular and Cellular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.
Hamilton RA; Department of Molecular and Cellular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.
Yi P; Department of Molecular and Cellular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.
Lonard DM; Department of Molecular and Cellular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.
Tsai MJ; Department of Molecular and Cellular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.
Tsai SY; Department of Molecular and Cellular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.
O'Malley BW; Department of Molecular and Cellular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA. Electronic address: berto@bcm.edu.

Mol Cell ; 70(4): 679-694.e7, 2018 05 17.

Article em En | MEDLINE | ID: mdl-29775582

Assuntos

Neoplasias da Mama/genética; Cromatina/metabolismo; Estrogênios/farmacologia; Regulação Neoplásica da Expressão Gênica; Coativador 3 de Receptor Nuclear/metabolismo; Transcrição Gênica; Sítios de Ligação; Neoplasias da Mama/metabolismo; Neoplasias da Mama/patologia; Cromatina/genética; Elementos Facilitadores Genéticos; Receptor alfa de Estrogênio/genética; Receptor alfa de Estrogênio/metabolismo; Feminino; Humanos; Coativador 3 de Receptor Nuclear/genética; Regiões Promotoras Genéticas; Ligação Proteica; Células Tumorais Cultivadas

Palavras-chave

ERα; SRC-3; eRNA; enhancer-promoter interaction; estrogen receptor-α; estrogen-induced transcription; looping determinant; steroid receptor coactivator-3

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transcrição Gênica / Neoplasias da Mama / Cromatina / Regulação Neoplásica da Expressão Gênica / Estrogênios / Coativador 3 de Receptor Nuclear Limite: Female / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google