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Further Studies to Support the Use of Coproporphyrin I and III as Novel Clinical Biomarkers for Evaluating the Potential for Organic Anion Transporting Polypeptide 1B1 and OATP1B3 Inhibition.
Shen, Hong; Christopher, Lisa; Lai, Yurong; Gong, Jiachang; Kandoussi, Hamza; Garonzik, Samira; Perera, Vidya; Garimella, Tushar; Humphreys, W Griffith.
Afiliação
  • Shen H; Metabolism and Pharmacokinetics (H.S., L.C., Y.L., J.G., W.G.H.), Bioanalytical Sciences (H.K.), and Clinical Pharmacology and Pharmacometrics (S.G., V.P., T.G.), Bristol-Myers Squibb Company, Princeton, New Jersey hong.shen1@bms.com.
  • Christopher L; Metabolism and Pharmacokinetics (H.S., L.C., Y.L., J.G., W.G.H.), Bioanalytical Sciences (H.K.), and Clinical Pharmacology and Pharmacometrics (S.G., V.P., T.G.), Bristol-Myers Squibb Company, Princeton, New Jersey.
  • Lai Y; Metabolism and Pharmacokinetics (H.S., L.C., Y.L., J.G., W.G.H.), Bioanalytical Sciences (H.K.), and Clinical Pharmacology and Pharmacometrics (S.G., V.P., T.G.), Bristol-Myers Squibb Company, Princeton, New Jersey.
  • Gong J; Metabolism and Pharmacokinetics (H.S., L.C., Y.L., J.G., W.G.H.), Bioanalytical Sciences (H.K.), and Clinical Pharmacology and Pharmacometrics (S.G., V.P., T.G.), Bristol-Myers Squibb Company, Princeton, New Jersey.
  • Kandoussi H; Metabolism and Pharmacokinetics (H.S., L.C., Y.L., J.G., W.G.H.), Bioanalytical Sciences (H.K.), and Clinical Pharmacology and Pharmacometrics (S.G., V.P., T.G.), Bristol-Myers Squibb Company, Princeton, New Jersey.
  • Garonzik S; Metabolism and Pharmacokinetics (H.S., L.C., Y.L., J.G., W.G.H.), Bioanalytical Sciences (H.K.), and Clinical Pharmacology and Pharmacometrics (S.G., V.P., T.G.), Bristol-Myers Squibb Company, Princeton, New Jersey.
  • Perera V; Metabolism and Pharmacokinetics (H.S., L.C., Y.L., J.G., W.G.H.), Bioanalytical Sciences (H.K.), and Clinical Pharmacology and Pharmacometrics (S.G., V.P., T.G.), Bristol-Myers Squibb Company, Princeton, New Jersey.
  • Garimella T; Metabolism and Pharmacokinetics (H.S., L.C., Y.L., J.G., W.G.H.), Bioanalytical Sciences (H.K.), and Clinical Pharmacology and Pharmacometrics (S.G., V.P., T.G.), Bristol-Myers Squibb Company, Princeton, New Jersey.
  • Humphreys WG; Metabolism and Pharmacokinetics (H.S., L.C., Y.L., J.G., W.G.H.), Bioanalytical Sciences (H.K.), and Clinical Pharmacology and Pharmacometrics (S.G., V.P., T.G.), Bristol-Myers Squibb Company, Princeton, New Jersey.
Drug Metab Dispos ; 46(8): 1075-1082, 2018 08.
Article em En | MEDLINE | ID: mdl-29777022
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Texto completo: 1 Eixos temáticos: Pesquisa_clinica Base de dados: MEDLINE Assunto principal: Transporte Biológico / Biomarcadores / Coproporfirinas / Transportadores de Ânions Orgânicos / Transportador 1 de Ânion Orgânico Específico do Fígado / Membro 1B3 da Família de Transportadores de Ânion Orgânico Carreador de Soluto Tipo de estudo: Prognostic_studies Limite: Adult / Humans / Male / Middle aged Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Eixos temáticos: Pesquisa_clinica Base de dados: MEDLINE Assunto principal: Transporte Biológico / Biomarcadores / Coproporfirinas / Transportadores de Ânions Orgânicos / Transportador 1 de Ânion Orgânico Específico do Fígado / Membro 1B3 da Família de Transportadores de Ânion Orgânico Carreador de Soluto Tipo de estudo: Prognostic_studies Limite: Adult / Humans / Male / Middle aged Idioma: En Ano de publicação: 2018 Tipo de documento: Article