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Enabling STD-NMR fragment screening using stabilized native GPCR: A case study of adenosine receptor.
Igonet, Sébastien; Raingeval, Claire; Cecon, Erika; Pucic-Bakovic, Maja; Lauc, Gordan; Cala, Olivier; Baranowski, Maciej; Perez, Javier; Jockers, Ralf; Krimm, Isabelle; Jawhari, Anass.
Afiliação
  • Igonet S; CALIXAR, 60 avenue Rockefeller, 69008, Lyon, France.
  • Raingeval C; Université de Lyon, Institut des Sciences Analytiques, UMR 5280, CNRS, Université Lyon 1, ENS Lyon - 5, rue de la Doua, F-69100, Villeurbanne, France.
  • Cecon E; Inserm, U1016, Institut Cochin, Paris, France.
  • Pucic-Bakovic M; CNRS UMR 8104, Paris, France.
  • Lauc G; University Paris Descartes, Sorbonne Paris Cité, Paris, France.
  • Cala O; GENOS, Borongajska cesta 83h, 10000, Zagreb, Croatia.
  • Baranowski M; GENOS, Borongajska cesta 83h, 10000, Zagreb, Croatia.
  • Perez J; Université de Lyon, Institut des Sciences Analytiques, UMR 5280, CNRS, Université Lyon 1, ENS Lyon - 5, rue de la Doua, F-69100, Villeurbanne, France.
  • Jockers R; SWING Beamline, Synchrotron SOLEIL, L'Orme des Merisiers, BP48, Saint-Aubin, Gif-sur-Yvette, F-91192, France.
  • Krimm I; SWING Beamline, Synchrotron SOLEIL, L'Orme des Merisiers, BP48, Saint-Aubin, Gif-sur-Yvette, F-91192, France.
  • Jawhari A; Inserm, U1016, Institut Cochin, Paris, France.
Sci Rep ; 8(1): 8142, 2018 05 25.
Article em En | MEDLINE | ID: mdl-29802269
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Espectroscopia de Ressonância Magnética / Receptor A2A de Adenosina / Avaliação Pré-Clínica de Medicamentos Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Espectroscopia de Ressonância Magnética / Receptor A2A de Adenosina / Avaliação Pré-Clínica de Medicamentos Tipo de estudo: Diagnostic_studies / Screening_studies Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article