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Monocyte-derived IL-1 and IL-6 are differentially required for cytokine-release syndrome and neurotoxicity due to CAR T cells.
Norelli, Margherita; Camisa, Barbara; Barbiera, Giulia; Falcone, Laura; Purevdorj, Ayurzana; Genua, Marco; Sanvito, Francesca; Ponzoni, Maurilio; Doglioni, Claudio; Cristofori, Patrizia; Traversari, Catia; Bordignon, Claudio; Ciceri, Fabio; Ostuni, Renato; Bonini, Chiara; Casucci, Monica; Bondanza, Attilio.
Afiliação
  • Norelli M; Innovative Immunotherapies Unit, San Raffaele Hospital Scientific Institute, Milano, Italy.
  • Camisa B; Vita-Salute San Raffaele University, Milano, Italy.
  • Barbiera G; Innovative Immunotherapies Unit, San Raffaele Hospital Scientific Institute, Milano, Italy.
  • Falcone L; Genomics of the Innate Immune System Unit, San Raffaele-Telethon Institute for Gene Therapy (SR-Tiget), Milano, Italy.
  • Purevdorj A; Innovative Immunotherapies Unit, San Raffaele Hospital Scientific Institute, Milano, Italy.
  • Genua M; Innovative Immunotherapies Unit, San Raffaele Hospital Scientific Institute, Milano, Italy.
  • Sanvito F; Genomics of the Innate Immune System Unit, San Raffaele-Telethon Institute for Gene Therapy (SR-Tiget), Milano, Italy.
  • Ponzoni M; Pathology Unit, San Raffaele Hospital Scientific Institute, Milano, Italy.
  • Doglioni C; Pathology Unit, San Raffaele Hospital Scientific Institute, Milano, Italy.
  • Cristofori P; Pathology Unit, San Raffaele Hospital Scientific Institute, Milano, Italy.
  • Traversari C; San-Raffaele-Telethon Institute for Gene Therapy (SR-Tiget), Milano, Italy.
  • Bordignon C; Molmed Spa, Milano, Italy.
  • Ciceri F; Vita-Salute San Raffaele University, Milano, Italy.
  • Ostuni R; Molmed Spa, Milano, Italy.
  • Bonini C; Vita-Salute San Raffaele University, Milano, Italy.
  • Casucci M; Hematology and Bone Marrow Transplantation Unit, San Raffaele Hospital Scientific Institute, Milano, Italy.
  • Bondanza A; Genomics of the Innate Immune System Unit, San Raffaele-Telethon Institute for Gene Therapy (SR-Tiget), Milano, Italy.
Nat Med ; 24(6): 739-748, 2018 06.
Article em En | MEDLINE | ID: mdl-29808007
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Monócitos / Imunoterapia Adotiva / Interleucina-6 / Interleucina-1 / Receptores de Antígenos Quiméricos / Neurotoxinas Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Monócitos / Imunoterapia Adotiva / Interleucina-6 / Interleucina-1 / Receptores de Antígenos Quiméricos / Neurotoxinas Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article