Your browser doesn't support javascript.
loading
Allogeneic haematopoietic cell transplantation for adult acute myeloid leukaemia in second remission: a retrospective study of the Adult Acute Myeloid Leukaemia Working Group of the Japan Society for Haematopoietic Cell Transplantation (JSHCT).
Konuma, Takaaki; Yanada, Masamitsu; Yamasaki, Satoshi; Kuwatsuka, Yachiyo; Fukuda, Takahiro; Kobayashi, Takeshi; Ozawa, Yukiyasu; Uchida, Naoyuki; Ota, Shuichi; Hoshino, Takumi; Takahashi, Satoshi; Kanda, Yoshinobu; Ueda, Yasunori; Takanashi, Minoko; Kanda, Junya; Ichinohe, Tatsuo; Atsuta, Yoshiko; Yano, Shingo.
Afiliação
  • Konuma T; Department of Haematology/Oncology, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
  • Yanada M; Department of Haematology, Fujita Health University School of Medicine, Toyoake, Japan.
  • Yamasaki S; Department of Haematology and Clinical Research Institute, National Hospital Organization Kyushu Medical Centre, Fukuoka, Japan.
  • Kuwatsuka Y; Centre for Advanced Medicine and Clinical Research, Nagoya University Hospital, Nagoya, Japan.
  • Fukuda T; Department of Haematopoietic Stem Cell Transplantation, National Cancer Centre Hospital, Tokyo, Japan.
  • Kobayashi T; Haematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Centre, Komagome Hospital, Tokyo, Japan.
  • Ozawa Y; Department of Haematology, Japanese Red Cross Nagoya First Hospital, Nagoya, Japan.
  • Uchida N; Department of Haematology, Federation of National Public Service Personnel Mutual Aid Associations Toranomon Hospital, Tokyo, Japan.
  • Ota S; Department of Haematology, Sapporo Hokuyu Hospital, Sapporo, Japan.
  • Hoshino T; Leukaemia Research Centre, Saiseikai Maebashi Hospital, Maebashi, Japan.
  • Takahashi S; Division of Molecular Therapy, The Advanced Clinical Research Centre, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
  • Kanda Y; Division of Haematology, Saitama Medical Centr, Jichi Medical University, Saitama, Japan.
  • Ueda Y; Department of Haematology and Oncology, Kurashiki Central Hospital, Kurashiki, Japan.
  • Takanashi M; Blood Service Headquarters, Japanese Red Cross Society, Tokyo, Japan.
  • Kanda J; Department of Haematology and Oncology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
  • Ichinohe T; Department of Haematology and Oncology, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan.
  • Atsuta Y; Japanese Data Centre for Haematopoietic Cell Transplantation, Nagoya, Japan.
  • Yano S; Department of Healthcare Administration, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Br J Haematol ; 182(2): 245-250, 2018 07.
Article em En | MEDLINE | ID: mdl-29808919
ABSTRACT
To evaluate the outcomes and prognostic factors following allogeneic haematopoietic cell transplantation (HCT) for adult acute myeloid leukaemia (AML) in second complete remission (CR2), we retrospectively analysed the Japanese registration data of 1080 adult AML patients in CR2 who had received allogeneic HCT. The probability of overall survival and the cumulative incidence of relapse at 3 years was 66% and 19%, respectively. In multivariate analysis, older age, poor cytogenetics and shorter duration of first complete remission were significantly associated with a higher overall mortality. Our data demonstrated the significant efficacy of allogeneic HCT for adult AML in CR2.
Assuntos
Palavras-chave
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Transplante de Células-Tronco Hematopoéticas Tipo de estudo: Etiology_studies / Evaluation_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Transplante de Células-Tronco Hematopoéticas Tipo de estudo: Etiology_studies / Evaluation_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2018 Tipo de documento: Article