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Improving cytidine and adenine base editors by expression optimization and ancestral reconstruction.
Koblan, Luke W; Doman, Jordan L; Wilson, Christopher; Levy, Jonathan M; Tay, Tristan; Newby, Gregory A; Maianti, Juan Pablo; Raguram, Aditya; Liu, David R.
Afiliação
  • Koblan LW; Merkin Institute of Transformative Technologies in Healthcare, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA.
  • Doman JL; Howard Hughes Medical Institute, Harvard University, Cambridge, Massachusetts, USA.
  • Wilson C; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts, USA.
  • Levy JM; Merkin Institute of Transformative Technologies in Healthcare, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA.
  • Tay T; Howard Hughes Medical Institute, Harvard University, Cambridge, Massachusetts, USA.
  • Newby GA; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts, USA.
  • Maianti JP; Merkin Institute of Transformative Technologies in Healthcare, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA.
  • Raguram A; Howard Hughes Medical Institute, Harvard University, Cambridge, Massachusetts, USA.
  • Liu DR; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts, USA.
Nat Biotechnol ; 36(9): 843-846, 2018 10.
Article em En | MEDLINE | ID: mdl-29813047
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: DNA / Adenina / Citidina Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: DNA / Adenina / Citidina Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article