The effect of PTC124 on choroideremia fibroblasts and iPSC-derived RPE raises considerations for therapy.

Torriano, Simona; Erkilic, Nejla; Baux, David; Cereso, Nicolas; De Luca, Valerie; Meunier, Isabelle; Moosajee, Mariya; Roux, Anne-Francoise; Hamel, Christian P; Kalatzis, Vasiliki

Torriano, Simona; Erkilic, Nejla; Baux, David; Cereso, Nicolas; De Luca, Valerie; Meunier, Isabelle; Moosajee, Mariya; Roux, Anne-Francoise; Hamel, Christian P; Kalatzis, Vasiliki.

Afiliação

Torriano S; Inserm U1051, Institute for Neurosciences of Montpellier, Montpellier, France.
Erkilic N; University of Montpellier, Montpellier, France.
Baux D; Inserm U1051, Institute for Neurosciences of Montpellier, Montpellier, France.
Cereso N; University of Montpellier, Montpellier, France.
De Luca V; Laboratory of Molecular Genetics, CHRU, Montpellier, France.
Meunier I; Inserm U1051, Institute for Neurosciences of Montpellier, Montpellier, France.
Moosajee M; University of Montpellier, Montpellier, France.
Roux AF; Inserm U1051, Institute for Neurosciences of Montpellier, Montpellier, France.
Hamel CP; University of Montpellier, Montpellier, France.
Kalatzis V; Inserm U1051, Institute for Neurosciences of Montpellier, Montpellier, France.

Sci Rep ; 8(1): 8234, 2018 05 29.

Article em En | MEDLINE | ID: mdl-29844446

Assuntos

Coroideremia/patologia; Células-Tronco Pluripotentes Induzidas/metabolismo; Oxidiazóis/farmacologia; Epitélio Pigmentado da Retina/metabolismo; Células Cultivadas; Fibroblastos/efeitos dos fármacos; Humanos; Epitélio Pigmentado da Retina/citologia

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oxidiazóis / Coroideremia / Epitélio Pigmentado da Retina / Células-Tronco Pluripotentes Induzidas Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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