An engineered combinatorial module of transcription factors boosts production of monoterpenoid indole alkaloids in Catharanthus roseus.

Schweizer, Fabian; Colinas, Maite; Pollier, Jacob; Van Moerkercke, Alex; Vanden Bossche, Robin; de Clercq, Rebecca; Goossens, Alain

Schweizer, Fabian; Colinas, Maite; Pollier, Jacob; Van Moerkercke, Alex; Vanden Bossche, Robin; de Clercq, Rebecca; Goossens, Alain.

Afiliação

Schweizer F; Ghent University, Department of Plant Biotechnology and Bioinformatics, 9052 Ghent, Belgium; VIB Center for Plant Systems Biology, 9052 Ghent, Belgium.
Colinas M; Ghent University, Department of Plant Biotechnology and Bioinformatics, 9052 Ghent, Belgium; VIB Center for Plant Systems Biology, 9052 Ghent, Belgium.
Pollier J; Ghent University, Department of Plant Biotechnology and Bioinformatics, 9052 Ghent, Belgium; VIB Center for Plant Systems Biology, 9052 Ghent, Belgium.
Van Moerkercke A; Ghent University, Department of Plant Biotechnology and Bioinformatics, 9052 Ghent, Belgium; VIB Center for Plant Systems Biology, 9052 Ghent, Belgium.
Vanden Bossche R; Ghent University, Department of Plant Biotechnology and Bioinformatics, 9052 Ghent, Belgium; VIB Center for Plant Systems Biology, 9052 Ghent, Belgium.
de Clercq R; Ghent University, Department of Plant Biotechnology and Bioinformatics, 9052 Ghent, Belgium; VIB Center for Plant Systems Biology, 9052 Ghent, Belgium.
Goossens A; Ghent University, Department of Plant Biotechnology and Bioinformatics, 9052 Ghent, Belgium; VIB Center for Plant Systems Biology, 9052 Ghent, Belgium. Electronic address: alain.goossens@psb.vib-ugent.be.

Metab Eng ; 48: 150-162, 2018 07.

Article em En | MEDLINE | ID: mdl-29852273

Assuntos

Apocynaceae; Engenharia Metabólica; Proteínas de Plantas; Plantas Geneticamente Modificadas; Alcaloides de Triptamina e Secologanina/metabolismo; Fatores de Transcrição; Apocynaceae/genética; Apocynaceae/metabolismo; Proteínas de Plantas/genética; Proteínas de Plantas/metabolismo; Plantas Geneticamente Modificadas/genética; Plantas Geneticamente Modificadas/metabolismo; Fatores de Transcrição/genética; Fatores de Transcrição/metabolismo

Palavras-chave

Jasmonate; MYC2; Madagascar periwinkle; Metabolic engineering; Monoterpenoid indole alkaloids; Transcription factor

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas de Plantas / Fatores de Transcrição / Plantas Geneticamente Modificadas / Apocynaceae / Alcaloides de Triptamina e Secologanina / Engenharia Metabólica Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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