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Helicase-Driven Activation of NFκB-COX2 Pathway Mediates the Immunosuppressive Component of dsRNA-Driven Inflammation in the Human Tumor Microenvironment.
Theodoraki, Marie-Nicole; Yerneni, Saigopalakrishna; Sarkar, Saumendra N; Orr, Brian; Muthuswamy, Ravikumar; Voyten, Jamie; Modugno, Francesmary; Jiang, Weijian; Grimm, Melissa; Basse, Per H; Bartlett, David L; Edwards, Robert P; Kalinski, Pawel.
Afiliação
  • Theodoraki MN; Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania.
  • Yerneni S; Department of Oto-Rhino-Laryngology, Head and Neck Surgery, University Medical Center, Ulm, Germany.
  • Sarkar SN; Department of Biomedical Engineering, College of Engineering, Carnegie Mellon University, Pittsburgh, PA.
  • Orr B; Department of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, Pennsylvania.
  • Muthuswamy R; University of Pittsburgh Cancer Institute, University of Pittsburgh, Pittsburgh, Pennsylvania.
  • Voyten J; Magee-Women's Research Institute, Ovarian Cancer Center of Excellence, Peritoneal/Ovarian Cancer Specialty Care Center, UPMC Hillman Cancer Center, and Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania.
  • Modugno F; Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania.
  • Jiang W; Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania.
  • Grimm M; University of Pittsburgh Cancer Institute, University of Pittsburgh, Pittsburgh, Pennsylvania.
  • Basse PH; Magee-Women's Research Institute, Ovarian Cancer Center of Excellence, Peritoneal/Ovarian Cancer Specialty Care Center, UPMC Hillman Cancer Center, and Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania.
  • Bartlett DL; Department of Medicine and Center for Immunotherapy, Roswell Park Cancer Institute, Buffalo, New York.
  • Edwards RP; Department of Medicine and Center for Immunotherapy, Roswell Park Cancer Institute, Buffalo, New York.
  • Kalinski P; Department of Medicine and Center for Immunotherapy, Roswell Park Cancer Institute, Buffalo, New York.
Cancer Res ; 78(15): 4292-4302, 2018 08 01.
Article em En | MEDLINE | ID: mdl-29853604
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: RNA de Cadeia Dupla / NF-kappa B / RNA Helicases / Ciclo-Oxigenase 2 / Microambiente Tumoral / Tolerância Imunológica / Inflamação Tipo de estudo: Prognostic_studies Limite: Adult / Aged / Animals / Female / Humans / Middle aged Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: RNA de Cadeia Dupla / NF-kappa B / RNA Helicases / Ciclo-Oxigenase 2 / Microambiente Tumoral / Tolerância Imunológica / Inflamação Tipo de estudo: Prognostic_studies Limite: Adult / Aged / Animals / Female / Humans / Middle aged Idioma: En Ano de publicação: 2018 Tipo de documento: Article