No answer to the lack of specificity: mouse monoclonal antibody targeting the angiotensin II type 1 receptor AT<sub>1</sub> fails to recognize its target.

Bouressam, Marie-Lynda; Lartaud, Isabelle; Dupuis, François; Lecat, Sandra

No answer to the lack of specificity: mouse monoclonal antibody targeting the angiotensin II type 1 receptor AT₁ fails to recognize its target.

Bouressam, Marie-Lynda; Lartaud, Isabelle; Dupuis, François; Lecat, Sandra.

Afiliação

Bouressam ML; Université de Lorraine, CITHEFOR, 54000, Nancy, France.
Lartaud I; Université de Lorraine, CITHEFOR, 54000, Nancy, France.
Dupuis F; Université de Lorraine, CITHEFOR, 54000, Nancy, France.
Lecat S; BSC UMR7242 "GPCRs, pain and inflammation" team, CNRS, Université de Strasbourg Labex Medalis, 67412, Illkirch, France. lecat@unistra.fr.

Naunyn Schmiedebergs Arch Pharmacol ; 391(8): 883-889, 2018 08.

Article em En | MEDLINE | ID: mdl-29868927

Assuntos

Anticorpos Monoclonais/farmacologia; Receptor Tipo 1 de Angiotensina/metabolismo; Animais; Células HEK293; Humanos; Camundongos; Receptor Tipo 1 de Angiotensina/genética; Receptor Tipo 1 de Angiotensina/imunologia; Transfecção

Palavras-chave

Angiotensin II type 1 receptor; Antibody; G protein-coupled receptors; Specificity

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptor Tipo 1 de Angiotensina / Anticorpos Monoclonais Limite: Animals / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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