Structural Basis of Protein-Protein Interactions between a trans-Acting Acyltransferase and Acyl Carrier Protein in Polyketide Disorazole Biosynthesis.

Miyanaga, Akimasa; Ouchi, Risako; Ishikawa, Fumihiro; Goto, Ena; Tanabe, Genzoh; Kudo, Fumitaka; Eguchi, Tadashi

Miyanaga, Akimasa; Ouchi, Risako; Ishikawa, Fumihiro; Goto, Ena; Tanabe, Genzoh; Kudo, Fumitaka; Eguchi, Tadashi.

Afiliação

Miyanaga A; Department of Chemistry , Tokyo Institute of Technology , 2-12-1, O-okayama , Meguro-ku, Tokyo 152-8551 , Japan.
Ouchi R; Department of Chemistry , Tokyo Institute of Technology , 2-12-1, O-okayama , Meguro-ku, Tokyo 152-8551 , Japan.
Ishikawa F; Faculty of Pharmacy , Kindai University , 3-4-1 Kowakae , Higashi-Osaka , Osaka 577-8502 , Japan.
Goto E; Department of Chemistry , Tokyo Institute of Technology , 2-12-1, O-okayama , Meguro-ku, Tokyo 152-8551 , Japan.
Tanabe G; Faculty of Pharmacy , Kindai University , 3-4-1 Kowakae , Higashi-Osaka , Osaka 577-8502 , Japan.
Kudo F; Department of Chemistry , Tokyo Institute of Technology , 2-12-1, O-okayama , Meguro-ku, Tokyo 152-8551 , Japan.
Eguchi T; Department of Chemistry , Tokyo Institute of Technology , 2-12-1, O-okayama , Meguro-ku, Tokyo 152-8551 , Japan.

J Am Chem Soc ; 140(25): 7970-7978, 2018 06 27.

Article em En | MEDLINE | ID: mdl-29870659

Assuntos

Proteína de Transporte de Acila/química; Aciltransferases/química; Azóis/metabolismo; Policetídeos/metabolismo; Aciltransferases/metabolismo; Azóis/química; Modelos Moleculares; Estrutura Molecular; Policetídeos/química; Ligação Proteica

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Azóis / Proteína de Transporte de Acila / Aciltransferases / Policetídeos Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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