Current approaches for the fitting and refinement of atomic models into cryo-EM maps using CCP-EM.

Nicholls, Robert A; Tykac, Michal; Kovalevskiy, Oleg; Murshudov, Garib N

Nicholls, Robert A; Tykac, Michal; Kovalevskiy, Oleg; Murshudov, Garib N.

Afiliação

Nicholls RA; Structural Studies, MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, England.
Tykac M; Structural Studies, MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, England.
Kovalevskiy O; Structural Studies, MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, England.
Murshudov GN; Structural Studies, MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 0QH, England.

Acta Crystallogr D Struct Biol ; 74(Pt 6): 492-505, 2018 Jun 01.

Article em En | MEDLINE | ID: mdl-29872001

Assuntos

Microscopia Crioeletrônica/métodos; Modelos Moleculares; Substâncias Macromoleculares/química; Conformação Proteica; Software

Palavras-chave

Divide and Conquer; ProSHADE; REFMAC5; cryo-EM; map blurring; map sharpening; model refinement; symmetry detection

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Modelos Moleculares / Microscopia Crioeletrônica Tipo de estudo: Qualitative_research Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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