Somatic Gene Transfer Using a Recombinant Adenoviral Vector (rAAV9) Encoding Pseudophosphorylated Human Thr175 Tau in Adult Rat Hippocampus Induces Tau Pathology.

Moszczynski, Alexander J; Gopaul, Jason; McCunn, Patrick; Volkening, Kathryn; Harvey, Madeline; Bartha, Robert; Schmid, Susanne; Strong, Michael J

Moszczynski, Alexander J; Gopaul, Jason; McCunn, Patrick; Volkening, Kathryn; Harvey, Madeline; Bartha, Robert; Schmid, Susanne; Strong, Michael J.

Afiliação

Moszczynski AJ; Department of Clinical Neurological Sciences, Molecular Medicine Group, Robarts Research Institute.
Gopaul J; Department of Anatomy and Cell Biology.
McCunn P; Department of Medical Biophysics.
Volkening K; Department of Clinical Neurological Sciences, Molecular Medicine Group, Robarts Research Institute.
Harvey M; Department of Clinical Neurological Sciences, Molecular Medicine Group, Robarts Research Institute.
Bartha R; Department of Medical Biophysics.
Schmid S; Department of Anatomy and Cell Biology.
Strong MJ; Department of Clinical Neurological Sciences, Molecular Medicine Group, Robarts Research Institute.

J Neuropathol Exp Neurol ; 77(8): 685-695, 2018 08 01.

Article em En | MEDLINE | ID: mdl-29878234

Assuntos

Adenoviridae/metabolismo; Técnicas de Transferência de Genes; Vetores Genéticos/metabolismo; Hipocampo/metabolismo; Treonina/metabolismo; Proteínas tau/metabolismo; Adenoviridae/genética; Animais; Feminino; Vetores Genéticos/genética; Hipocampo/patologia; Humanos; Fosforilação/fisiologia; Ratos; Ratos Sprague-Dawley; Reflexo de Sobressalto/fisiologia; Treonina/genética; Proteínas tau/genética

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Treonina / Adenoviridae / Proteínas tau / Técnicas de Transferência de Genes / Vetores Genéticos / Hipocampo Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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