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A new therapeutic avenue for bronchiectasis: Dry powder inhaler of ciprofloxacin nanoplex exhibits superior ex vivo mucus permeability and antibacterial efficacy to its native ciprofloxacin counterpart.
Tran, The-Thien; Vidaillac, Celine; Yu, Hong; Yong, Valerie F L; Roizman, Dan; Chandrasekaran, Ravishankar; Lim, Albert Y H; Low, Teck Boon; Tan, Gan Liang; Abisheganaden, John A; Koh, Mariko Siyue; Teo, Jeanette; Chotirmall, Sanjay H; Hadinoto, Kunn.
Afiliação
  • Tran TT; School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore 637459, Singapore.
  • Vidaillac C; Singapore Centre for Environmental Life Sciences Engineering, Nanyang Technological University, Singapore.
  • Yu H; School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore 637459, Singapore.
  • Yong VFL; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore.
  • Roizman D; Singapore Centre for Environmental Life Sciences Engineering, Nanyang Technological University, Singapore.
  • Chandrasekaran R; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore.
  • Lim AYH; Department of Respiratory and Critical Care Medicine, Tan Tock Seng Hospital, Singapore.
  • Low TB; Department of Respiratory and Critical Care Medicine, Changi General Hospital, Singapore.
  • Tan GL; Department of Respiratory and Critical Care Medicine, Singapore General Hospital, Singapore.
  • Abisheganaden JA; Department of Respiratory and Critical Care Medicine, Tan Tock Seng Hospital, Singapore.
  • Koh MS; Department of Respiratory and Critical Care Medicine, Singapore General Hospital, Singapore; Duke-National University of Singapore Medical School, Singapore.
  • Teo J; Department of Laboratory Medicine, National University Hospital, Singapore.
  • Chotirmall SH; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore.
  • Hadinoto K; School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore 637459, Singapore. Electronic address: kunnong@ntu.edu.sg.
Int J Pharm ; 547(1-2): 368-376, 2018 Aug 25.
Article em En | MEDLINE | ID: mdl-29886096

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pseudomonas aeruginosa / Bronquiectasia / Ciprofloxacina / Antibacterianos Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pseudomonas aeruginosa / Bronquiectasia / Ciprofloxacina / Antibacterianos Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article