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Uncoupling ITIM receptor G6b-B from tyrosine phosphatases Shp1 and Shp2 disrupts murine platelet homeostasis.
Geer, Mitchell J; van Geffen, Johanna P; Gopalasingam, Piraveen; Vögtle, Timo; Smith, Christopher W; Heising, Silke; Kuijpers, Marijke J E; Tullemans, Bibian M E; Jarvis, Gavin E; Eble, Johannes A; Jeeves, Mark; Overduin, Michael; Heemskerk, Johan W M; Mazharian, Alexandra; Senis, Yotis A.
Afiliação
  • Geer MJ; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.
  • van Geffen JP; Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands.
  • Gopalasingam P; Henry Wellcome Building for Biomolecular NMR Spectroscopy, University of Birmingham, Birmingham, United Kingdom.
  • Vögtle T; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.
  • Smith CW; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.
  • Heising S; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.
  • Kuijpers MJE; Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands.
  • Tullemans BME; Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands.
  • Jarvis GE; Department of Physiology, Development, and Neuroscience, University of Cambridge, Cambridge, United Kingdom; and.
  • Eble JA; Institute of Physiological Chemistry and Pathobiochemistry, University of Münster, Münster, Germany.
  • Jeeves M; Henry Wellcome Building for Biomolecular NMR Spectroscopy, University of Birmingham, Birmingham, United Kingdom.
  • Overduin M; Henry Wellcome Building for Biomolecular NMR Spectroscopy, University of Birmingham, Birmingham, United Kingdom.
  • Heemskerk JWM; Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands.
  • Mazharian A; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.
  • Senis YA; Institute of Cardiovascular Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom.
Blood ; 132(13): 1413-1425, 2018 09 27.
Article em En | MEDLINE | ID: mdl-29891536
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Trombocitopenia / Plaquetas / Receptores Imunológicos / Proteína Tirosina Fosfatase não Receptora Tipo 6 / Proteína Tirosina Fosfatase não Receptora Tipo 11 Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Trombocitopenia / Plaquetas / Receptores Imunológicos / Proteína Tirosina Fosfatase não Receptora Tipo 6 / Proteína Tirosina Fosfatase não Receptora Tipo 11 Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2018 Tipo de documento: Article