Reduced telomere length in offspring of old fathers in a long-lived seabird.
Biol Lett
; 14(6)2018 06.
Article
em En
| MEDLINE
| ID: mdl-29899134
ABSTRACT
Evidence for transgenerational effects of senescence, whereby offspring from older parents have a reduced lifetime reproductive success, is increasing. Such effects could arise from compromised germline maintenance in old parents, potentially reflected in reduced telomere length in their offspring. We test the relationship between parental age and offspring early-life telomere length in a natural population of common terns and find a significant negative correlation between paternal age and offspring telomere length. Offspring telomere length is reduced by 35 base pairs for each additional year of paternal age. We find no correlation with maternal age. These results fit with the idea of compromised germline maintenance in males, whose germline stem cells require continued division.
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Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Envelhecimento
/
Charadriiformes
/
Encurtamento do Telômero
Limite:
Animals
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article