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Safety and efficacy of upadacitinib in patients with rheumatoid arthritis and inadequate response to conventional synthetic disease-modifying anti-rheumatic drugs (SELECT-NEXT): a randomised, double-blind, placebo-controlled phase 3 trial.
Burmester, Gerd R; Kremer, Joel M; Van den Bosch, Filip; Kivitz, Alan; Bessette, Louis; Li, Yihan; Zhou, Yijie; Othman, Ahmed A; Pangan, Aileen L; Camp, Heidi S.
Afiliação
  • Burmester GR; Charité-Universitätsmedizin, Berlin, Germany. Electronic address: gerd.burmester@charite.de.
  • Kremer JM; Albany Medical College, Albany, NY, USA.
  • Van den Bosch F; VIB-UGent Center for Inflammation Research, Department of Internal Medicine, Ghent University, Ghent, Belgium; Department of Rheumatology, Ghent University Hospital, Ghent, Belgium.
  • Kivitz A; Altoona Center for Clinical Research, Duncansville, PA, USA.
  • Bessette L; Laval University, Quebec, QC, Canada.
  • Li Y; AbbVie Inc, North Chicago, IL, USA.
  • Zhou Y; AbbVie Inc, North Chicago, IL, USA.
  • Othman AA; AbbVie Inc, North Chicago, IL, USA.
  • Pangan AL; AbbVie Inc, North Chicago, IL, USA.
  • Camp HS; AbbVie Inc, North Chicago, IL, USA.
Lancet ; 391(10139): 2503-2512, 2018 06 23.
Article em En | MEDLINE | ID: mdl-29908669
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Artrite Reumatoide / Inibidores de Janus Quinases / Compostos Heterocíclicos com 3 Anéis Tipo de estudo: Clinical_trials Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Artrite Reumatoide / Inibidores de Janus Quinases / Compostos Heterocíclicos com 3 Anéis Tipo de estudo: Clinical_trials Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2018 Tipo de documento: Article