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Nitroimidazole-based inhibitors DTP338 and DTP348 are safe for zebrafish embryos and efficiently inhibit the activity of human CA IX in Xenopus oocytes.
Aspatwar, Ashok; Becker, Holger M; Parvathaneni, Nanda Kumar; Hammaren, Milka; Svorjova, Aleksandra; Barker, Harlan; Supuran, Claudiu T; Dubois, Ludwig; Lambin, Philippe; Parikka, Mataleena; Parkkila, Seppo; Winum, Jean-Yves.
Afiliação
  • Aspatwar A; a Faculty of Medicine and Life Sciences , University of Tampere , Tampere , Finland.
  • Becker HM; b Department of Physiological Chemistry , University of Veterinary Medicine Hannover , Hannover , Germany.
  • Parvathaneni NK; c Department of Radiotherapy, The M-Lab Group, GROW - School for Oncology and Developmental Biology , Maastricht University Medical Centre , Maastricht , The Netherlands.
  • Hammaren M; d Institut des Biomolécules Max Mousseron (IBMM) UMR 5247 CNRS, ENSCM , Université de Montpellier , Montpellier Cedex 05 , France.
  • Svorjova A; a Faculty of Medicine and Life Sciences , University of Tampere , Tampere , Finland.
  • Barker H; a Faculty of Medicine and Life Sciences , University of Tampere , Tampere , Finland.
  • Supuran CT; a Faculty of Medicine and Life Sciences , University of Tampere , Tampere , Finland.
  • Dubois L; e NEUROFARBA Department, Section of Pharmaceutical and Nutraceutical Sciences , University of Florence , Polo Scientifico , Firenze , Italy.
  • Lambin P; c Department of Radiotherapy, The M-Lab Group, GROW - School for Oncology and Developmental Biology , Maastricht University Medical Centre , Maastricht , The Netherlands.
  • Parikka M; c Department of Radiotherapy, The M-Lab Group, GROW - School for Oncology and Developmental Biology , Maastricht University Medical Centre , Maastricht , The Netherlands.
  • Parkkila S; a Faculty of Medicine and Life Sciences , University of Tampere , Tampere , Finland.
  • Winum JY; a Faculty of Medicine and Life Sciences , University of Tampere , Tampere , Finland.
J Enzyme Inhib Med Chem ; 33(1): 1064-1073, 2018 Dec.
Article em En | MEDLINE | ID: mdl-29909747
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oócitos / Inibidores da Anidrase Carbônica / Anidrase Carbônica IX / Nitroimidazóis Limite: Animals / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oócitos / Inibidores da Anidrase Carbônica / Anidrase Carbônica IX / Nitroimidazóis Limite: Animals / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article