A proteomic analysis unravels novel CORVET and HOPS proteins involved in Toxoplasma gondii secretory organelles biogenesis.

Morlon-Guyot, Juliette; El Hajj, Hiba; Martin, Kevin; Fois, Adrien; Carrillo, Amandine; Berry, Laurence; Burchmore, Richard; Meissner, Markus; Lebrun, Maryse; Daher, Wassim

Morlon-Guyot, Juliette; El Hajj, Hiba; Martin, Kevin; Fois, Adrien; Carrillo, Amandine; Berry, Laurence; Burchmore, Richard; Meissner, Markus; Lebrun, Maryse; Daher, Wassim.

Afiliação

Morlon-Guyot J; Dynamique des Interactions Membranaires Normales et Pathologiques, UMR5235 CNRS, INSERM, Université de Montpellier, Montpellier, France.
El Hajj H; Departments of Internal Medicine and Experimental Pathology, Immunology and Microbiology, American University of Beirut, Beirut, Lebanon.
Martin K; Dynamique des Interactions Membranaires Normales et Pathologiques, UMR5235 CNRS, INSERM, Université de Montpellier, Montpellier, France.
Fois A; Dynamique des Interactions Membranaires Normales et Pathologiques, UMR5235 CNRS, INSERM, Université de Montpellier, Montpellier, France.
Carrillo A; Dynamique des Interactions Membranaires Normales et Pathologiques, UMR5235 CNRS, INSERM, Université de Montpellier, Montpellier, France.
Berry L; Dynamique des Interactions Membranaires Normales et Pathologiques, UMR5235 CNRS, INSERM, Université de Montpellier, Montpellier, France.
Burchmore R; Polyomics Facility, University of Glasgow, Glasgow, UK.
Meissner M; Wellcome Centre for Molecular Parasitology, University of Glasgow, Glasgow, UK.
Lebrun M; Department of Veterinary Sciences, Experimental Parasitology, Ludwig-Maximilians-Universität München, Munich, Germany.
Daher W; Dynamique des Interactions Membranaires Normales et Pathologiques, UMR5235 CNRS, INSERM, Université de Montpellier, Montpellier, France.

Cell Microbiol ; 20(11): e12870, 2018 Nov.

Article em En | MEDLINE | ID: mdl-29911335

Assuntos

Complexos Multiproteicos/metabolismo; Proteínas de Protozoários/metabolismo; Toxoplasma/citologia; Toxoplasma/metabolismo; Compartimento Celular; Proteínas de Fluorescência Verde/genética; Proteínas de Fluorescência Verde/metabolismo; Complexos Multiproteicos/genética; Mutação; Biogênese de Organelas; Subunidades Proteicas; Transporte Proteico; Proteômica/métodos; Proteínas de Protozoários/genética; Proteínas de Transporte Vesicular/genética; Proteínas de Transporte Vesicular/metabolismo

Palavras-chave

Apicomplexa; BEACH domain-containing protein; CORVET; HOPS; Tet-inducible system; Toxoplasma gondii; Vps8; anterograde trafficking; invasion; membranous fusion and fission events; secretory organelles

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Toxoplasma / Proteínas de Protozoários / Complexos Multiproteicos Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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