A Recombinant Fragment of Human Surfactant Protein D induces Apoptosis in Pancreatic Cancer Cell Lines <i>via</i> Fas-Mediated Pathway.

Kaur, Anuvinder; Riaz, Muhammad Suleman; Murugaiah, Valarmathy; Varghese, Praveen Mathews; Singh, Shiv K; Kishore, Uday

A Recombinant Fragment of Human Surfactant Protein D induces Apoptosis in Pancreatic Cancer Cell Lines via Fas-Mediated Pathway.

Kaur, Anuvinder; Riaz, Muhammad Suleman; Murugaiah, Valarmathy; Varghese, Praveen Mathews; Singh, Shiv K; Kishore, Uday.

Afiliação

Kaur A; Biosciences, College of Health and Life Sciences, Brunel University London, Uxbridge, United Kingdom.
Riaz MS; Biosciences, College of Health and Life Sciences, Brunel University London, Uxbridge, United Kingdom.
Murugaiah V; Biosciences, College of Health and Life Sciences, Brunel University London, Uxbridge, United Kingdom.
Varghese PM; Biosciences, College of Health and Life Sciences, Brunel University London, Uxbridge, United Kingdom.
Singh SK; Department of Gastroenterology and Gastrointestinal Oncology, University Medical Center, Goettingen, Germany.
Kishore U; Biosciences, College of Health and Life Sciences, Brunel University London, Uxbridge, United Kingdom.

Front Immunol ; 9: 1126, 2018.

Article em En | MEDLINE | ID: mdl-29915574

Assuntos

Apoptose/efeitos dos fármacos; Neoplasias Pancreáticas/metabolismo; Fragmentos de Peptídeos/farmacologia; Proteína D Associada a Surfactante Pulmonar/farmacologia; Transdução de Sinais/efeitos dos fármacos; Receptor fas/metabolismo; Apoptose/genética; Caspase 3/metabolismo; Caspase 8/metabolismo; Pontos de Checagem do Ciclo Celular/efeitos dos fármacos; Pontos de Checagem do Ciclo Celular/genética; Linhagem Celular Tumoral; Humanos; NF-kappa B/metabolismo; Transporte Proteico; Proteína D Associada a Surfactante Pulmonar/química; Proteínas Recombinantes; Serina-Treonina Quinases TOR/metabolismo; Proteína Supressora de Tumor p53/genética; Proteína Supressora de Tumor p53/metabolismo; Receptor fas/genética; Neoplasias Pancreáticas

Palavras-chave

apoptosis; immune surveillance; innate immunity; pancreatic cancer; surfactant protein D

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Fragmentos de Peptídeos / Transdução de Sinais / Apoptose / Receptor fas / Proteína D Associada a Surfactante Pulmonar Limite: Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

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