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U-BIOPRED: evaluation of the value of a public-private partnership to industry.
Riley, John H; Erpenbeck, Veit J; Matthews, John G; Holweg, Cecile T J; Compton, Christopher; Seibold, Wolfgang; Higenbottam, Timothy; Wagers, Scott; Rowe, Anthony; Myles, David.
Afiliação
  • Riley JH; GlaxoSmithKline, Respiratory Therapy Area, Gunnels Wood Road, Stevenage, UK. Electronic address: john.h.riley@gsk.com.
  • Erpenbeck VJ; Novartis Pharma AG, Basel, Switzerland.
  • Matthews JG; Genentech Inc., South San Francisco, CA, USA.
  • Holweg CTJ; Genentech Inc., South San Francisco, CA, USA.
  • Compton C; GlaxoSmithKline, Respiratory Franchise, Brentford, UK.
  • Seibold W; Boehringer Ingelheim Pharma, GmbH & Co. KG, Biberach, Germany.
  • Higenbottam T; Allergy Therapeutics, Research and Development, Worthing, UK.
  • Wagers S; BioSci Consulting, Rijksweg, Belgium.
  • Rowe A; Jansen Pharmaceuticals, Johnson and Johnson, Philadelphia, PA, USA.
  • Myles D; GlaxoSmithKline, Respiratory Therapy Area, Gunnels Wood Road, Stevenage, UK.
Drug Discov Today ; 23(9): 1622-1634, 2018 09.
Article em En | MEDLINE | ID: mdl-29936248
ABSTRACT
Unbiased Biomarkers for the Prediction of Respiratory Disease Outcomes (U-BIOPRED) was initiated in the first year of the Innovative Medicines Initiative (IMI). It was an ambitious plan to tackle the understanding of asthma through an integration of clinical and multi-'omics approaches that necessitated the bringing together of industry, academic, and patient representatives because it was too large to be managed by any one of the partners in isolation. It was a novel experience for all concerned. In this review, we describe the main features of the U-BIOPRED experience from the industry perspective. We list some of the key advantages and learnings from the perspective of the authors, and also improvements that we feel could be made in future projects.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Asma / Biomarcadores / Antiasmáticos / Indústria Farmacêutica / Descoberta de Drogas / Parcerias Público-Privadas Tipo de estudo: Diagnostic_studies / Evaluation_studies / Guideline / Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Asma / Biomarcadores / Antiasmáticos / Indústria Farmacêutica / Descoberta de Drogas / Parcerias Público-Privadas Tipo de estudo: Diagnostic_studies / Evaluation_studies / Guideline / Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2018 Tipo de documento: Article