Acquisition of Beta-Lactamase by Neisseria meningitidis through Possible Horizontal Gene Transfer.
Antimicrob Agents Chemother
; 62(9)2018 09.
Article
em En
| MEDLINE
| ID: mdl-29941641
ABSTRACT
We report the detection in France of a beta-lactamase-producing invasive meningococcal isolate. Whole-genome sequencing of the isolate revealed a ROB-1-type beta-lactamase gene that is frequently encountered in Haemophilus influenzae, suggesting horizontal transfer between isolates of these bacterial species. Beta-lactamases are exceptional in meningococci, with no reports for more than 2 decades. This report is worrying, as the expansion of such isolates may jeopardize the effective treatment against invasive meningococcal disease.
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Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Beta-Lactamases
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Haemophilus influenzae
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Transferência Genética Horizontal
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Neisseria meningitidis
Limite:
Adult
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Female
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Humans
País como assunto:
Europa
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article