The Shielding Effect of Microcrystalline Cellulose on Drug Nanocrystal Particles During Compaction.

Liu, Yang; Xiao, Hanyang; Xie, Jin; Zhang, Zengzhu; Ma, Yueqin; Yue, Pengfei; Yang, Ming

Liu, Yang; Xiao, Hanyang; Xie, Jin; Zhang, Zengzhu; Ma, Yueqin; Yue, Pengfei; Yang, Ming.

Afiliação

Liu Y; Jiangxi University of Traditional Chinese Medicine, 1688 MEILINGDADAO Road, Nanchang, 330004, China.
Xiao H; Department of Pharmaceutics, 94th Hospital of People's Liberation Army, Nanchang, China.
Xie J; Jiangxi University of Traditional Chinese Medicine, 1688 MEILINGDADAO Road, Nanchang, 330004, China.
Zhang Z; Department of Pharmaceutics, 94th Hospital of People's Liberation Army, Nanchang, China.
Ma Y; Department of Pharmaceutics, 94th Hospital of People's Liberation Army, Nanchang, China.
Yue P; Jiangxi University of Traditional Chinese Medicine, 1688 MEILINGDADAO Road, Nanchang, 330004, China. feigleyue@outlook.com.
Yang M; Jiangxi University of Traditional Chinese Medicine, 1688 MEILINGDADAO Road, Nanchang, 330004, China.

AAPS PharmSciTech ; 19(6): 2488-2498, 2018 Aug.

Article em En | MEDLINE | ID: mdl-29948978

Assuntos

Celulose/química; Nanopartículas/química; Comprimidos/química; Excipientes/química; Tamanho da Partícula; Pressão

Palavras-chave

compaction; composite particles; interstitial rearrangement; microcrystalline cellulose; nanocrystals

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Comprimidos / Celulose / Nanopartículas Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo

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XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Comprimidos / Celulose / Nanopartículas Idioma: En Ano de publicação: 2018 Tipo de documento: Article