Persistent hypoglycemia associated with lipid storage myopathy in a paint foal.
J Vet Intern Med
; 32(4): 1442-1446, 2018 Jul.
Article
em En
| MEDLINE
| ID: mdl-29957835
ABSTRACT
A 12-hours-old Paint filly was examined because of weakness and dull mentation after birth. Despite IV administered dextrose, the foal remained persistently hypoglycemic with increase in serum activity of muscle and liver enzymes. A postmortem diagnosis of lipid myopathy most similar to multiple acyl-CoA dehydrogenase deficiency (MADD) was confirmed by findings of myofiber lipid accumulation, elevated urine organic acids, and serum free acylcarnitines with respect to control foals. This report details a case of equine neonatal lipid storage myopathy with many biochemical characteristics of MADD. Lipid storage myopathies should be included as a differential diagnosis in foals with persistent weakness and hypoglycemia.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Doenças dos Cavalos
/
Hipoglicemia
/
Erros Inatos do Metabolismo Lipídico
Tipo de estudo:
Diagnostic_studies
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Risk_factors_studies
Limite:
Animals
Idioma:
En
Ano de publicação:
2018
Tipo de documento:
Article