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Activity of translation regulator eukaryotic elongation factor-2 kinase is increased in Parkinson disease brain and its inhibition reduces alpha synuclein toxicity.
Jan, Asad; Jansonius, Brandon; Delaidelli, Alberto; Bhanshali, Forum; An, Yi Andy; Ferreira, Nelson; Smits, Lisa M; Negri, Gian Luca; Schwamborn, Jens C; Jensen, Poul H; Mackenzie, Ian R; Taubert, Stefan; Sorensen, Poul H.
Afiliação
  • Jan A; Aarhus Institute of Advanced Studies, Department of Biomedicine, Aarhus University, Høegh-Guldbergs Gade 6B, DK-8000, Aarhus, Denmark. ajan@aias.au.dk.
  • Jansonius B; British Columbia Cancer Research Centre, 675 West 10th Avenue, Vancouver, BC, V5Z 1L3, Canada.
  • Delaidelli A; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada.
  • Bhanshali F; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital Research Institute, Department of Medical Genetics, University of British Columbia, Vancouver, BC, V5Z 4H4, Canada.
  • An YA; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital Research Institute, Department of Medical Genetics, University of British Columbia, Vancouver, BC, V5Z 4H4, Canada.
  • Ferreira N; Danish Research Institute of Translational Neuroscience, Department of Biomedicine, Aarhus University, Ole Worms Allé 3, DK-8000, Aarhus, Denmark.
  • Smits LM; Developmental and Cellular Biology, Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 7, avenue des Hauts-Fourneaux, 4362, Esch-sur-Alzette, Luxembourg.
  • Negri GL; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada.
  • Schwamborn JC; Developmental and Cellular Biology, Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, 7, avenue des Hauts-Fourneaux, 4362, Esch-sur-Alzette, Luxembourg.
  • Jensen PH; Danish Research Institute of Translational Neuroscience, Department of Biomedicine, Aarhus University, Ole Worms Allé 3, DK-8000, Aarhus, Denmark.
  • Mackenzie IR; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada.
  • Taubert S; Centre for Molecular Medicine and Therapeutics, BC Children's Hospital Research Institute, Department of Medical Genetics, University of British Columbia, Vancouver, BC, V5Z 4H4, Canada.
  • Sorensen PH; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada. psor@mail.ubc.ca.
Acta Neuropathol Commun ; 6(1): 54, 2018 07 02.
Article em En | MEDLINE | ID: mdl-29961428
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Encéfalo / Alfa-Sinucleína / Quinase do Fator 2 de Elongação Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2018 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Encéfalo / Alfa-Sinucleína / Quinase do Fator 2 de Elongação Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2018 Tipo de documento: Article