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Chemical synthesis, characterisation and in vitro and in vivo metabolism of the synthetic opioid MT-45 and its newly identified fluorinated analogue 2F-MT-45 with metabolite confirmation in urine samples from known drug users.
McKenzie, Craig; Sutcliffe, Oliver B; Read, Kevin D; Scullion, Paul; Epemolu, Ola; Fletcher, Daniel; Helander, Anders; Beck, Olof; Rylski, Alexia; Antonides, Lysbeth H; Riley, Jennifer; Smith, Shannah A; Nic Daeid, Niamh.
Afiliação
  • McKenzie C; 1Forensic Drug Research Centre, Centre for Anatomy and Human Identification, School of Science and Engineering, University of Dundee, Dundee, UK.
  • Sutcliffe OB; 2Division of Chemistry and Environmental Science, School of Science and the Environment, Manchester Metropolitan University, Manchester, UK.
  • Read KD; 3Drug Discovery Unit, School of Life Sciences, University of Dundee, Dundee, UK.
  • Scullion P; 3Drug Discovery Unit, School of Life Sciences, University of Dundee, Dundee, UK.
  • Epemolu O; 3Drug Discovery Unit, School of Life Sciences, University of Dundee, Dundee, UK.
  • Fletcher D; 3Drug Discovery Unit, School of Life Sciences, University of Dundee, Dundee, UK.
  • Helander A; 4Department of Laboratory Medicine, Karolinska Institutet and Karolinska University Laboratory, Stockholm, Sweden.
  • Beck O; 4Department of Laboratory Medicine, Karolinska Institutet and Karolinska University Laboratory, Stockholm, Sweden.
  • Rylski A; 4Department of Laboratory Medicine, Karolinska Institutet and Karolinska University Laboratory, Stockholm, Sweden.
  • Antonides LH; 1Forensic Drug Research Centre, Centre for Anatomy and Human Identification, School of Science and Engineering, University of Dundee, Dundee, UK.
  • Riley J; 2Division of Chemistry and Environmental Science, School of Science and the Environment, Manchester Metropolitan University, Manchester, UK.
  • Smith SA; 5Leverhulme Research Centre for Forensic Science, School of Science and Engineering, University of Dundee, Dundee, UK.
  • Nic Daeid N; 3Drug Discovery Unit, School of Life Sciences, University of Dundee, Dundee, UK.
Forensic Toxicol ; 36(2): 359-374, 2018.
Article em En | MEDLINE | ID: mdl-29963206

Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Guideline / Risk_factors_studies Idioma: En Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Guideline / Risk_factors_studies Idioma: En Ano de publicação: 2018 Tipo de documento: Article